Flourescent Switch Constructed Based on Hemin-Sensitive Anionic Conjugated Polymer and Its Applications in DNA-Related Sensors
文献类型：期刊论文
| 作者 | Li, Bingling; Qin, Chuanjiang; Li, Tao; Wang, Lixiang1; Dong, Shaojun |
| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2009-05-01 |
| 卷号 | 81期号:9页码:3544-3550 |
| ISSN号 | 0003-2700 |
| DOI | 10.1021/ac900110a |
| 英文摘要 | Here, a fluorescent switch is constructed combining hemin, hemin aptamer, and a newly synthesized anionic conjugated polymer (ACP), poly(9,9-bis(6'-phosphate-hexyl) fluorenealt-1,4-phenylene) sodium salt (PFHPNa/PFP). In the "off-state", the fluorescence of PFP is sensitively quenched by hemin, with a high K(sv) value of similar to 10(7). While in the "on-state", the formation of the aptamer/hemin complex recovers the fluorescence intensity. The fluorescent switch is sensitive and selective to hemin. To testify the universality and practicality of the fluorescent switch, a series of label-free DNA-related sensing platforms are developed, containing three DNA sensing strategies and one ATP recognition strategy. The fluorescent switch developed is simple, sensitive, and universal, which extends applications of the anionic conjugated polymers. |
| 语种 | 英语 |
| WOS记录号 | WOS:000265632400047 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/67973]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, Lixiang |
| 作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, Grad Sch, State Key Lab Electroanalyt Chem, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Changchun Inst Appl Chem, Grad Sch, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Bingling,Qin, Chuanjiang,Li, Tao,et al. Flourescent Switch Constructed Based on Hemin-Sensitive Anionic Conjugated Polymer and Its Applications in DNA-Related Sensors[J]. ANALYTICAL CHEMISTRY,2009,81(9):3544-3550. |
| APA | Li, Bingling,Qin, Chuanjiang,Li, Tao,Wang, Lixiang,&Dong, Shaojun.(2009).Flourescent Switch Constructed Based on Hemin-Sensitive Anionic Conjugated Polymer and Its Applications in DNA-Related Sensors.ANALYTICAL CHEMISTRY,81(9),3544-3550. |
| MLA | Li, Bingling,et al."Flourescent Switch Constructed Based on Hemin-Sensitive Anionic Conjugated Polymer and Its Applications in DNA-Related Sensors".ANALYTICAL CHEMISTRY 81.9(2009):3544-3550. |
入库方式： OAI收割
来源：化学研究所
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