The Surface Modification of Hydroxyapatite Nanoparticles by the Ring Opening Polymerization of gamma-Benzyl-L-glutamate N-carboxyanhydride
文献类型：期刊论文
| 作者 | Wei, Junchao1,2; Liu, Aixue1,2; Chen, Lei1,2; Zhang, Peibiao1,2; Chen, Xuesi1,2; Jing, Xiabin1,2 |
| 刊名 | MACROMOLECULAR BIOSCIENCE
 |
| 出版日期 | 2009-07-07 |
| 卷号 | 9期号:7页码:631-638 |
| 关键词 | Biomaterials Hydroxyapatite Nanoparticles Ring-opening Polymerization Surface Modification |
| ISSN号 | 1616-5187 |
| DOI | 10.1002/mabi.200800324 |
| 英文摘要 | The surface modification of hydroxyapatite (HA) nanoparticles by the ring opening polymerization (ROP) of gamma-benzyl-L-glutamate N-carboxyanhydride (BLG-NCA) was proposed to prepare the poly(gamma-benzyl-L-glutamate) (PBLG)-grafted HA nanoparticles (PBLG-g-HA) for the first time. HA nanoparticles were firstly treated by 3-aminopropylthriethoxysilane (APS) and then the terminal amino groups of the modified HA particles initiated the ROP of BLG-NCA to obtain PBLG-g-HA. The process was monitored by XPS and FT-IR. The surface grafting amounts of PBLG on HA ranging from 12.1 to 43.1% were characterized by thermal gravimetric analysis (TGA). The powder X-ray diffraction (XRD) analysis confirmed that the ROP only underwent on the surface of HA nanoparticles without changing its bulk properties. The SEM measurement showed that the PBLG-g-HA hybrid could form an interpenetrating net structure in the self-assembly process. The PBLG-g-HA hybrid could maintain higher colloid stability than the pure HA nanoparticles. The in vitro cell cultures suggested the cell adhesion ability of PBLG-g-HA was much higher than that of pure HA. |
| 语种 | 英语 |
| WOS记录号 | WOS:000267962700001 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/68005]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wei, Junchao |
| 作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wei, Junchao,Liu, Aixue,Chen, Lei,et al. The Surface Modification of Hydroxyapatite Nanoparticles by the Ring Opening Polymerization of gamma-Benzyl-L-glutamate N-carboxyanhydride[J]. MACROMOLECULAR BIOSCIENCE,2009,9(7):631-638. |
| APA | Wei, Junchao,Liu, Aixue,Chen, Lei,Zhang, Peibiao,Chen, Xuesi,&Jing, Xiabin.(2009).The Surface Modification of Hydroxyapatite Nanoparticles by the Ring Opening Polymerization of gamma-Benzyl-L-glutamate N-carboxyanhydride.MACROMOLECULAR BIOSCIENCE,9(7),631-638. |
| MLA | Wei, Junchao,et al."The Surface Modification of Hydroxyapatite Nanoparticles by the Ring Opening Polymerization of gamma-Benzyl-L-glutamate N-carboxyanhydride".MACROMOLECULAR BIOSCIENCE 9.7(2009):631-638. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。