Smart polyelectrolyte microcapsules as carriers for water-soluble small molecular drug
文献类型：期刊论文
| 作者 | Song, Weixing1,2; He, Qiang1,2; Moehwald, Helmuth2; Yang, Yang3; Li, Junbai1 |
| 刊名 | JOURNAL OF CONTROLLED RELEASE
 |
| 出版日期 | 2009-10-15 |
| 卷号 | 139期号:2页码:160-166 |
| 关键词 | Smart Capsule Water-soluble Drug Encapsulation Layer-by-layer Assembly |
| ISSN号 | 0168-3659 |
| DOI | 10.1016/j.jconrel.2009.06.010 |
| 英文摘要 | Heat treatment is introduced as a simple method for the encapsulation of low molecular weight water-soluble drugs within layer-by-layer assembled microcapsules. A water-soluble drug, procainamide hydrochloride, could thus be encapsulated in large amount and enriched by more than 2 orders of magnitude in the assembled PDADMAC/PSS capsules. The shrunk capsules could control the unloading rate of drugs, and the drugs could be easily unloaded using ultrasonic treatment. The encapsulated amount could be quantitatively controlled via the drug concentration in the bulk. We also found that smaller capsules possess higher encapsulation capability. (C) 2009 Elsevier B.V. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000271344200011 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/68037]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Li, Junbai |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, BNLMS, Int Joint Lab, Beijing 100190, Peoples R China 2.Max Planck Inst Colloids & Interfaces, D-14476 Golm, Germany 3.Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Song, Weixing,He, Qiang,Moehwald, Helmuth,et al. Smart polyelectrolyte microcapsules as carriers for water-soluble small molecular drug[J]. JOURNAL OF CONTROLLED RELEASE,2009,139(2):160-166. |
| APA | Song, Weixing,He, Qiang,Moehwald, Helmuth,Yang, Yang,&Li, Junbai.(2009).Smart polyelectrolyte microcapsules as carriers for water-soluble small molecular drug.JOURNAL OF CONTROLLED RELEASE,139(2),160-166. |
| MLA | Song, Weixing,et al."Smart polyelectrolyte microcapsules as carriers for water-soluble small molecular drug".JOURNAL OF CONTROLLED RELEASE 139.2(2009):160-166. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。