Research on Characterization and Biocompatibility of Nano-bacterial Cellulose Membrane
文献类型：期刊论文
| 作者 | Wang Zong-Liang1,2; Jia Yuan-Yuan3; Shi Yi1; Cong Deng-Li1; Chen Yan-Yan1; Jia Shi-Ru4; Zhou Yu-Lai1 |
| 刊名 | CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
 |
| 出版日期 | 2009-08-10 |
| 卷号 | 30期号:8页码:1553-1558 |
| 关键词 | Bacterial Cellulose Biocompatibility Tissue Engineering Scaffold |
| ISSN号 | 0251-0790 |
| 英文摘要 | Bacterial cellulose membrane, possessing nanofibers, an ultrafine 3-dimensional network and proper porosity, was prepared by static culture of Acetobacter xylinum and characterized by light microscope, SEM (Scanning electron microscope) and AFM (Atomic force microscope). The results show that BC has extremely fine network of nano-structure, the pore size of freeze-dried BC is 0.6 to 2.8 mu m; the width of cellulose is 50 to 80 nm. By measuring their dry weight and wet weight, the porosities of air-dried BC and freeze-dried BC were determined, respectively. The porosity of air-dried and freeze-dried BC is about 70% and 90%, respectively. The water vapor permeability of air-dried BC is quite excellent because the existence of a large number of hydroxyl. BC co-culture with fibroblasts (FBs) and chondrocytes, respectively, and subcutaneous implant of FBs-BC composition into nude mouse. The composition is well intergrated into the skin of nude mouse. FBs and chondrocytes form continuous cell layer on the surface of BC and the expression of GFP is normally. The results demonstrate that BC membrane is suitable for cell attachment and proliferation, and shows better biocompatibility. It is expected to become a promising tissue engineering scaffold. |
| 语种 | 英语 |
| WOS记录号 | WOS:000269601000015 |
| 出版者 | HIGHER EDUCATION PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/68295]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zhou Yu-Lai |
| 作者单位 | 1.Jilin Univ, Coll Pharmaceut Sci, Changchun 130021, Peoples R China 2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 3.Tianjin Sci & Technol Univ, Coll Mat Sci & Chem Engn, Tianjin 300457, Peoples R China 4.Tianjin Sci & Technol Univ, Minist Educ, Key Lab Ind Microbiol, Tianjin 300457, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang Zong-Liang,Jia Yuan-Yuan,Shi Yi,et al. Research on Characterization and Biocompatibility of Nano-bacterial Cellulose Membrane[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2009,30(8):1553-1558. |
| APA | Wang Zong-Liang.,Jia Yuan-Yuan.,Shi Yi.,Cong Deng-Li.,Chen Yan-Yan.,...&Zhou Yu-Lai.(2009).Research on Characterization and Biocompatibility of Nano-bacterial Cellulose Membrane.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,30(8),1553-1558. |
| MLA | Wang Zong-Liang,et al."Research on Characterization and Biocompatibility of Nano-bacterial Cellulose Membrane".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 30.8(2009):1553-1558. |
入库方式： OAI收割
来源：化学研究所
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