Double-Network Hydrogel with High Mechanical Strength Prepared from Two Biocompatible Polymers
文献类型：期刊论文
| 作者 | Zhang, Xiaoyan1; Guo, Xinglin1; Yang, Shuguan1; Tan, Shuaixia1; Li, Xiaofeng1; Dai, Hongjun1; Yu, Xiaolan1; Zhang, Xiaoli1; Weng, Ning2,3; Jian, Bin2,3 |
| 刊名 | JOURNAL OF APPLIED POLYMER SCIENCE
 |
| 出版日期 | 2009-06-05 |
| 卷号 | 112期号:5页码:3063-3070 |
| 关键词 | Biocompatibility High Performance Polymers Hydrogels Mechanical Properties Networks |
| ISSN号 | 0021-8995 |
| DOI | 10.1002/app.29572 |
| 英文摘要 | Novel double-network (DN) hydrogels with high mechanical strength have been fabricated with two biocompatible polymers, poly(vinyl alcohol) (PVA) and poly(ethylene glycol) (PEG), through a simple freezing and thawing method. Some properties of the obtained hydrogels, such as the mechanical strength, rheological and thermodynamic behavior, drug release, and morphology, have been characterized. The results reveal that in sharp contrast to most common hydrogels made with simple natural or synthetic polymers, PVA/PEG hydrogels can sustain a compressive pressure as high as several megapascals, highlighting their potential application as biomedical materials. In addition, a model for describing the structural formation of PVA/PEG DN hydrogels is proposed: the condensed PVA-rich phase forms microcrystals first, which bridge with one another to form a rigid and inhomogeneous net backbone to support the shape of the hydrogel, and then the dilute PEG-rich phase partially crystallizes among the cavities or voids of the backbone; meanwhile, there are entanglements of molecular chains between the two polymers. Moreover, a mechanism is also proposed to explain the high mechanical strength of PVA/PEG DN hydrogels. It is suggested that the free motion of PEG clusters in the cavities of PVA networks can prevent the crack from growing to a macroscopic level because the linear PEG chains in the cavities effectively absorb the crack energy and relax the local stress either by viscous dissipation or by large deformation of the PEG chains. (c) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 112: 3063-3070, 2009 |
| 语种 | 英语 |
| WOS记录号 | WOS:000265076100057 |
| 出版者 | JOHN WILEY & SONS INC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/68407]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Xu, Jian |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China 2.301 Hosp, Beijing 100853, Peoples R China 3.Baoding Hosp, Beijing 100853, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Xiaoyan,Guo, Xinglin,Yang, Shuguan,et al. Double-Network Hydrogel with High Mechanical Strength Prepared from Two Biocompatible Polymers[J]. JOURNAL OF APPLIED POLYMER SCIENCE,2009,112(5):3063-3070. |
| APA | Zhang, Xiaoyan.,Guo, Xinglin.,Yang, Shuguan.,Tan, Shuaixia.,Li, Xiaofeng.,...&Xu, Jian.(2009).Double-Network Hydrogel with High Mechanical Strength Prepared from Two Biocompatible Polymers.JOURNAL OF APPLIED POLYMER SCIENCE,112(5),3063-3070. |
| MLA | Zhang, Xiaoyan,et al."Double-Network Hydrogel with High Mechanical Strength Prepared from Two Biocompatible Polymers".JOURNAL OF APPLIED POLYMER SCIENCE 112.5(2009):3063-3070. |
入库方式： OAI收割
来源：化学研究所
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