Complex of shikonin and beta-cyclodextrins by using supercritical carbon dioxide
文献类型：期刊论文
| 作者 | He, Jun |
| 刊名 | JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY
 |
| 出版日期 | 2009-04-01 |
| 卷号 | 63期号:3-4页码:249-255 |
| 关键词 | Shikonin Methyl-beta-cyclodextrin 2-hydroxypropyl-beta-cyclodextrin Complex Supercritical Carbon Dioxide |
| ISSN号 | 0923-0750 |
| DOI | 10.1007/s10847-008-9514-5 |
| 英文摘要 | In this work, the complex of shikonin-methyl-beta-cyclodextrin and shikonin-2-hydroxypropyl-beta-cyclodextrin were studied in supercritical carbon dioxide (sc CO(2)) at moderate pressure and temperature much lower than the melting point of shikonin. For comparing, the complex was also prepared by sealed heating method. Complex efficiency between shikonin and 2-hydroxypropyl-beta-cyclodextrin (HPBCD) was quite low. Partly formation of shikonin-methyl-beta-cyclodextrin (MBCD) was obtained by sealed heating method. Complete formation of shikonin-MBCD was obtained in sc CO(2) media in short reaction time. This complexation was accelerated and enhanced by the rise in both the reaction temperature and carbon dioxide pressure up to 100 A degrees C 100 bar. The physical state of cyclodextrins in complex reaction has remarkable influence on the complex. The aqueous solubility of shikonin could be enhanced about 75 times by complexing with MBCD. |
| 语种 | 英语 |
| WOS记录号 | WOS:000264548400008 |
| 出版者 | SPRINGER |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/68605]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | He, Jun |
| 作者单位 | Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Jun. Complex of shikonin and beta-cyclodextrins by using supercritical carbon dioxide[J]. JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY,2009,63(3-4):249-255. |
| APA | He, Jun.(2009).Complex of shikonin and beta-cyclodextrins by using supercritical carbon dioxide.JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY,63(3-4),249-255. |
| MLA | He, Jun."Complex of shikonin and beta-cyclodextrins by using supercritical carbon dioxide".JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY 63.3-4(2009):249-255. |
入库方式： OAI收割
来源：化学研究所
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