Preliminary studies of Tc-99m-BnAO and its analogues: synthesis, radiolabeling and in vitro cell uptake
文献类型：期刊论文
| 作者 | Sun, Xin; Chu, Taiwei; Wang, Xiangyun |
| 刊名 | NUCLEAR MEDICINE AND BIOLOGY
 |
| 出版日期 | 2010-02-01 |
| 卷号 | 37期号:2页码:117-123 |
| 关键词 | Bnao Labeling Technetium-99m Hypoxia Marker Lipophilicity Cellular Accumulation |
| ISSN号 | 0969-8051 |
| DOI | 10.1016/j.nucmedbio.2009.09.003 |
| 英文摘要 | Introduction: Tc-99m-BnAO is one of the nonnitroimidazole hypoxia markers with the highest citation and could be potentially useful in both oncology and other clinical applications. However, it appears inferior in vitro due to lower absolute accumulation and smaller anoxic/normoxic uptake ratio. It is possible that the analogues of Tc-99m-BnAO have higher hypoxia selectivity after the ligand of Tc-99m-BnAO is modified. |
| 语种 | 英语 |
| WOS记录号 | WOS:000274947300002 |
| 出版者 | ELSEVIER SCIENCE INC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/68749]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Chu, Taiwei |
| 作者单位 | Peking Univ, Coll Chem & Mol Engn, Dept Appl Chem, BNLMS, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Xin,Chu, Taiwei,Wang, Xiangyun. Preliminary studies of Tc-99m-BnAO and its analogues: synthesis, radiolabeling and in vitro cell uptake[J]. NUCLEAR MEDICINE AND BIOLOGY,2010,37(2):117-123. |
| APA | Sun, Xin,Chu, Taiwei,&Wang, Xiangyun.(2010).Preliminary studies of Tc-99m-BnAO and its analogues: synthesis, radiolabeling and in vitro cell uptake.NUCLEAR MEDICINE AND BIOLOGY,37(2),117-123. |
| MLA | Sun, Xin,et al."Preliminary studies of Tc-99m-BnAO and its analogues: synthesis, radiolabeling and in vitro cell uptake".NUCLEAR MEDICINE AND BIOLOGY 37.2(2010):117-123. |
入库方式： OAI收割
来源：化学研究所
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