Logic gates and pH sensing devices based on a supramolecular telomere DNA/conjugated polymer system
文献类型：期刊论文
| 作者 | Pu, Fang1,2,3; Wang, Chunyan1,2,3; Hu, Dan1,2,3; Huang, Zhenzhen1,2,3; Ren, Jinsong1,2; Wang, Shu4; Qu, Xiaogang1,2 |
| 刊名 | MOLECULAR BIOSYSTEMS
 |
| 出版日期 | 2010 |
| 卷号 | 6期号:10页码:1928-1932 |
| ISSN号 | 1742-206X |
| DOI | 10.1039/c004215c |
| 英文摘要 | A conceptually new class of telomere DNA/conjugated polymer system has been constructed to enable sensing of pH changes and create robust logic gates capable of multiplex logic operations. It combines the advantages of quadruplex-duplex conversion and efficient energy transfer from the polymer to the DNA binding molecule. The system is simple in design, fast in operation, and allows the detection of pH changes with high accuracy and sensitivity. In addition, the approach could be adopted for the investigation of other biomolecular conformational changes upon binding to their targets. More importantly, the present logic operations showed advantages over other nucleic acid-based logic gates: (1) The system does not require any CP modification or oligonucleotide labeling, which offers the advantages of simplicity and cost efficiency. (2) The reversibility of the switch makes the logic gates feasible to realize system reset. (3) The system could be implemented to perform multiple logic functions by using distinct input signals. |
| 语种 | 英语 |
| WOS记录号 | WOS:000281772300025 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/68773]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Ren, Jinsong |
| 作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, Biol Chem Lab, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Rare Earth Resources Utilizat, Changchun 130022, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100190, Peoples R China 4.Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Pu, Fang,Wang, Chunyan,Hu, Dan,et al. Logic gates and pH sensing devices based on a supramolecular telomere DNA/conjugated polymer system[J]. MOLECULAR BIOSYSTEMS,2010,6(10):1928-1932. |
| APA | Pu, Fang.,Wang, Chunyan.,Hu, Dan.,Huang, Zhenzhen.,Ren, Jinsong.,...&Qu, Xiaogang.(2010).Logic gates and pH sensing devices based on a supramolecular telomere DNA/conjugated polymer system.MOLECULAR BIOSYSTEMS,6(10),1928-1932. |
| MLA | Pu, Fang,et al."Logic gates and pH sensing devices based on a supramolecular telomere DNA/conjugated polymer system".MOLECULAR BIOSYSTEMS 6.10(2010):1928-1932. |
入库方式： OAI收割
来源：化学研究所
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