Water-Soluble Conjugated Polymers for Fluorescent-Enzyme Assays
文献类型:期刊论文
作者 | Feng, Fude; Liu, Libing; Yang, Qiong; Wang, Shu |
刊名 | MACROMOLECULAR RAPID COMMUNICATIONS
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出版日期 | 2010-08-17 |
卷号 | 31期号:16页码:1405-1421 |
关键词 | Conjugated Polymers Enzyme Assays Fluorescence Fret Probes Superquenching |
ISSN号 | 1022-1336 |
DOI | 10.1002/marc.201000020 |
英文摘要 | Enzyme assays are receiving more and more research and application interest because of the rapidly increasing demands of clinical diagnosis, environmental analysis, drug discovery, and molecular biology. Water-soluble light-harvesting conjugated polymers (CPs) coordinate the action of a large number of absorbing units to afford an amplified fluorescence signal, which makes them useful as optical platforms in highly sensitive chemical and biological sensors. This Feature Article highlights recent developments of water-soluble CPs for fluorescent assays of enzymes. Different signal transduction mechanisms, such as electron transfer, fluorescence resonance energy transfer (FRET), and aggregation or conformation changes of CPs, are employed in these assays according to the dissimilar nature of enzymes. Potential challenges and future research directions in these approaches based on CPs are also discussed. |
语种 | 英语 |
WOS记录号 | WOS:000281346900001 |
出版者 | WILEY-V C H VERLAG GMBH |
源URL | [http://ir.iccas.ac.cn/handle/121111/68917] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Wang, Shu |
作者单位 | Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Feng, Fude,Liu, Libing,Yang, Qiong,et al. Water-Soluble Conjugated Polymers for Fluorescent-Enzyme Assays[J]. MACROMOLECULAR RAPID COMMUNICATIONS,2010,31(16):1405-1421. |
APA | Feng, Fude,Liu, Libing,Yang, Qiong,&Wang, Shu.(2010).Water-Soluble Conjugated Polymers for Fluorescent-Enzyme Assays.MACROMOLECULAR RAPID COMMUNICATIONS,31(16),1405-1421. |
MLA | Feng, Fude,et al."Water-Soluble Conjugated Polymers for Fluorescent-Enzyme Assays".MACROMOLECULAR RAPID COMMUNICATIONS 31.16(2010):1405-1421. |
入库方式: OAI收割
来源:化学研究所
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