Enantioselective Synthesis of Spirocyclic Oxindole-beta-lactones via N-Heterocyclic Carbene-Catalyzed Cycloaddition of Ketenes and Isatins
文献类型:期刊论文
作者 | Wang, Xiao-Na; Zhang, Yan-Yong; Ye, Song |
刊名 | ADVANCED SYNTHESIS & CATALYSIS
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出版日期 | 2010-08-01 |
卷号 | 352期号:11-12页码:1892-1895 |
关键词 | Asymmetric Catalysis Cycloaddition Indoles Ketenes N-heterocyclic Carbenes |
ISSN号 | 1615-4150 |
DOI | 10.1002/adsc.201000187 |
英文摘要 | Chiral N-heterocyclic carbenes were found to be efficient catalysts for the formal [2+2] cycloaddition reaction of disubstituted ketenes and isatins to give the corresponding spirocyclic oxindole-beta-lactones in good yields with good diastereoselectivities and excellent enantioselectivities Ring opening with Grignard reagents or decarboxylation of the oxindole spirocyclic-beta-lactone gave the corresponding 3-hydroxy- or 3-alkylenyloxindoles in good yields |
语种 | 英语 |
WOS记录号 | WOS:000281654500015 |
出版者 | WILEY-BLACKWELL |
源URL | [http://ir.iccas.ac.cn/handle/121111/69963] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Ye, Song |
作者单位 | Chinese Acad Sci, Beijing Natl Lab Mol Sci, CAS Key Lab Mol Recognit & Funct, Inst Chem, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Wang, Xiao-Na,Zhang, Yan-Yong,Ye, Song. Enantioselective Synthesis of Spirocyclic Oxindole-beta-lactones via N-Heterocyclic Carbene-Catalyzed Cycloaddition of Ketenes and Isatins[J]. ADVANCED SYNTHESIS & CATALYSIS,2010,352(11-12):1892-1895. |
APA | Wang, Xiao-Na,Zhang, Yan-Yong,&Ye, Song.(2010).Enantioselective Synthesis of Spirocyclic Oxindole-beta-lactones via N-Heterocyclic Carbene-Catalyzed Cycloaddition of Ketenes and Isatins.ADVANCED SYNTHESIS & CATALYSIS,352(11-12),1892-1895. |
MLA | Wang, Xiao-Na,et al."Enantioselective Synthesis of Spirocyclic Oxindole-beta-lactones via N-Heterocyclic Carbene-Catalyzed Cycloaddition of Ketenes and Isatins".ADVANCED SYNTHESIS & CATALYSIS 352.11-12(2010):1892-1895. |
入库方式: OAI收割
来源:化学研究所
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