Chiral Amine Thiourea-Promoted Enantioselective Michael Addition Reactions of 3-Substituted Benzofuran-2(3H)-ones to Maleimides
文献类型：期刊论文
| 作者 | Li, Xin1,2; Hu, Shenshen3; Xi, Zhiguo1,2; Zhang, Long3; Luo, Sanzhong3; Cheng, Jin-Pei1,2 |
| 刊名 | JOURNAL OF ORGANIC CHEMISTRY
 |
| 出版日期 | 2010-12-17 |
| 卷号 | 75期号:24页码:8697-8700 |
| ISSN号 | 0022-3263 |
| DOI | 10.1021/j0101832e |
| 英文摘要 | A highly diastereo- and enantioselective Michael addition reaction with respect to prochiral 3-substituted benzofuran-2(3H)-ones and maleimides by a chiral bifunctional thiourea-tertiary amine catalyst was investigated. The corresponding adducts, containing a quaternary center at the C3-position of the benzofuran-2(3H)-one as well as a vicinal tertiary center, were generally obtained in high yields (up to 99%) with very good diastereo- (up to > 20:1 dr) and enantioselectivities (up to 97% cc). |
| 语种 | 英语 |
| WOS记录号 | WOS:000285081100048 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/70551]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Li, Xin |
| 作者单位 | 1.Nankai Univ, Dept Chem, Tianjin 300071, Peoples R China 2.Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China 3.Chinese Acad Sci, Beijing Natl Lab Mol Sci, CAS Key Lab Mol Recognit & Funct, Inst Chem, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Xin,Hu, Shenshen,Xi, Zhiguo,et al. Chiral Amine Thiourea-Promoted Enantioselective Michael Addition Reactions of 3-Substituted Benzofuran-2(3H)-ones to Maleimides[J]. JOURNAL OF ORGANIC CHEMISTRY,2010,75(24):8697-8700. |
| APA | Li, Xin,Hu, Shenshen,Xi, Zhiguo,Zhang, Long,Luo, Sanzhong,&Cheng, Jin-Pei.(2010).Chiral Amine Thiourea-Promoted Enantioselective Michael Addition Reactions of 3-Substituted Benzofuran-2(3H)-ones to Maleimides.JOURNAL OF ORGANIC CHEMISTRY,75(24),8697-8700. |
| MLA | Li, Xin,et al."Chiral Amine Thiourea-Promoted Enantioselective Michael Addition Reactions of 3-Substituted Benzofuran-2(3H)-ones to Maleimides".JOURNAL OF ORGANIC CHEMISTRY 75.24(2010):8697-8700. |
入库方式： OAI收割
来源：化学研究所
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