Mono-dispersed bioactive glass nanospheres: Preparation and effects on biomechanics of mammalian cells
文献类型：期刊论文
| 作者 | Hong, Zhongkui1,2; Luz, Gisela M.3; Hampel, Paul J.2; Jin, Minshan2; Liu, Aixue1; Chen, Xuesi1; Mano, Joao F.3 |
| 刊名 | JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
 |
| 出版日期 | 2010-12-01 |
| 卷号 | 95A期号:3页码:747-754 |
| 关键词 | Bioactive Glass Biomechanics Bone Marrow Stem Cells Aortic Endothelial Cells Afm |
| ISSN号 | 1549-3296 |
| DOI | 10.1002/jbm.a.32898 |
| 英文摘要 | Mono-dispersed SiO2-CaO bioactive glass nanospheres (BGNS) were prepared by a two step sol-gel method in the absence of surfactant. The size of BGNS ranged from 200 to 350 nm in diameter and exhibited a rough surface texture. In vitro biomineralization tests showed that BGNS could rapidly induce the deposition of an apatite layer in simulated body fluid (SEW). The effect of bioactive glass on the biomechanical properties of various mammalian cells was first reported in this paper. Atomic force microscopy (AFM) was used for measuring the biomechanical properties of mammalian cells. The result showed that BGNS-medium could significantly decrease the plasma membrane stiffness of bone marrow stem cells (BMSCs) by similar to 50% and stimulate BMSCs spreading. The effect of BGNS on biomechanical properties of bovine aortic endothelial cells (BAECs) was opposite to that on BMSCs. BGNS increased the BAECs' stiffness and stimulated the elongation of endothelial cells and the formation of endothelial networks, which might potentially facilitate the vascularization of implanted BGNS-based biomaterials in tissue engineering as a scaffold or as an injectable system. (C) 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 95A: 747-754, 2010. |
| 语种 | 英语 |
| WOS记录号 | WOS:000283959800011 |
| 出版者 | WILEY-BLACKWELL |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/70637]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Hong, Zhongkui |
| 作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 2.Univ Missouri, Dept Phys & Astron, Columbia, MO 65211 USA 3.Univ Minho, Headquarters European Inst Excellence Tissue Engn, Dept Polymer Engn, Res Grp Biomat Biodegradables & Biomimet 3B, P-4806909 Caldas Das Taipas, Guimaraes, Portugal |
| 推荐引用方式 GB/T 7714 | Hong, Zhongkui,Luz, Gisela M.,Hampel, Paul J.,et al. Mono-dispersed bioactive glass nanospheres: Preparation and effects on biomechanics of mammalian cells[J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,2010,95A(3):747-754. |
| APA | Hong, Zhongkui.,Luz, Gisela M..,Hampel, Paul J..,Jin, Minshan.,Liu, Aixue.,...&Mano, Joao F..(2010).Mono-dispersed bioactive glass nanospheres: Preparation and effects on biomechanics of mammalian cells.JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,95A(3),747-754. |
| MLA | Hong, Zhongkui,et al."Mono-dispersed bioactive glass nanospheres: Preparation and effects on biomechanics of mammalian cells".JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A 95A.3(2010):747-754. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。