Towards Characteristics of Photodynamic Drugs Specifically Aimed at Microvascular Diseases
文献类型：期刊论文
| 作者 | Zhao, Jingquan1; Deng, Hong1; Xie, Jie1; Liu, Xin1; Zhang, Yang1; Huang, Naiyan2; Gu, Ying2 |
| 刊名 | MINI-REVIEWS IN MEDICINAL CHEMISTRY
 |
| 出版日期 | 2010-04-01 |
| 卷号 | 10期号:4页码:332-341 |
| 关键词 | Photodynamic Therapy (Pdt) Photosensitizers Solid Tumor Microvascular Disease Target-related Characteristic Drug Drug Delivery Biological Activity Drug Preparation |
| ISSN号 | 1389-5575 |
| 英文摘要 | Photodynamic therapy (PDT) is a versatile methodology to treat various diseases but the drugs (photosensitizers) specifically aimed at individual character of diseases are urgently needed. Among those, the perilenoquinoid photosensitizers were thought of low PDT effectiveness to solid tumors due to low absorption on the "photodynamic window" but may be specially suitable for PDT to some microvascular diseases, such as age-related macular degeneration (AMD) and port wine stains (PWS), as well as other superficial diseases. Two strategies were discussed to convert the photosensitizers into clinically acceptable drugs in consideration of the drug-delivery and biological activity. |
| 语种 | 英语 |
| WOS记录号 | WOS:000277886300006 |
| 出版者 | BENTHAM SCIENCE PUBL LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/70973]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zhao, Jingquan |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Key Lab Photochem, BNLMS, Beijing 100190, Peoples R China 2.Chinese Peoples Liberat Army Gen Hosp, Dept Laser Med, Beijing 100853, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Jingquan,Deng, Hong,Xie, Jie,et al. Towards Characteristics of Photodynamic Drugs Specifically Aimed at Microvascular Diseases[J]. MINI-REVIEWS IN MEDICINAL CHEMISTRY,2010,10(4):332-341. |
| APA | Zhao, Jingquan.,Deng, Hong.,Xie, Jie.,Liu, Xin.,Zhang, Yang.,...&Gu, Ying.(2010).Towards Characteristics of Photodynamic Drugs Specifically Aimed at Microvascular Diseases.MINI-REVIEWS IN MEDICINAL CHEMISTRY,10(4),332-341. |
| MLA | Zhao, Jingquan,et al."Towards Characteristics of Photodynamic Drugs Specifically Aimed at Microvascular Diseases".MINI-REVIEWS IN MEDICINAL CHEMISTRY 10.4(2010):332-341. |
入库方式： OAI收割
来源：化学研究所
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