Gadolinium(III) chelated conjugated polymer as a potential MRI contrast agent
文献类型：期刊论文
| 作者 | Xu, Qingling1; Zhu, Litao2; Yu, Minghui1; Feng, Fude1; An, Lingling1; Xing, Chengfen1; Wang, Shu1 |
| 刊名 | POLYMER
 |
| 出版日期 | 2010-03-11 |
| 卷号 | 51期号:6页码:1336-1340 |
| 关键词 | Conjugated Polymers Synthesis Mri Contrast Agent |
| ISSN号 | 0032-3861 |
| DOI | 10.1016/j.polymer.2009.04.003 |
| 英文摘要 | Nuclear magnetic resonance imaging (MRI) has become a powerful technique in clinical diagnostics. In this work, a new MRI contrast agent by covalently linking Gd(III) chelates to the side chain of conjugated polymer (PF-Gd) is synthesized by Suzuki cross-coupling reaction. The PF-Gd exhibits a higher relaxivity and a pronounced enhancement in contrast than that of (NMG)(2)-Gd-DTPA widely used for clinical diagnosis. This work should be feasible to potentially lead to a new class of imaging contrast agents (C) 2009 Elsevier Ltd. All rights reserved |
| 语种 | 英语 |
| WOS记录号 | WOS:000275743300017 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/71089]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, Shu |
| 作者单位 | 1.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Key Lab Organ Solids, Inst Chem, Beijing 100190, Peoples R China 2.Beijing Normal Univ, State Key Lab Cognit Neurosci & Learning, Beijing 100875, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Qingling,Zhu, Litao,Yu, Minghui,et al. Gadolinium(III) chelated conjugated polymer as a potential MRI contrast agent[J]. POLYMER,2010,51(6):1336-1340. |
| APA | Xu, Qingling.,Zhu, Litao.,Yu, Minghui.,Feng, Fude.,An, Lingling.,...&Wang, Shu.(2010).Gadolinium(III) chelated conjugated polymer as a potential MRI contrast agent.POLYMER,51(6),1336-1340. |
| MLA | Xu, Qingling,et al."Gadolinium(III) chelated conjugated polymer as a potential MRI contrast agent".POLYMER 51.6(2010):1336-1340. |
入库方式： OAI收割
来源：化学研究所
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