Pulling Genetic RNA out of Tobacco Mosaic Virus Using Single-Molecule Force Spectroscopy
文献类型：期刊论文
| 作者 | Liu, Ningning1; Peng, Bo2; Lin, Yuan2,3,4; Su, Zhaohui2; Niu, Zhongwei3,4; Wang, Qian3,4; Zhang, Wenke1; Li, Hongbin5; Shen, Jiacong1 |
| 刊名 | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
 |
| 出版日期 | 2010-08-18 |
| 卷号 | 132期号:32页码:11036-11038 |
| ISSN号 | 0002-7863 |
| DOI | 10.1021/ja1052544 |
| 英文摘要 | RNA-coat protein interactions in intact tobacco mosaic virus have been investigated for the first time directly on the single-molecule level by pulling the genetic RNA step by step out of the helical groove formed by its protein coat. The effects of pulling speed and pH on RNA-protein interactions are presented. In addition, the rebinding behavior of the detached RNA with the protein coat is discussed. Our results demonstrate the possibility of studying nucleic acid-protein interactions in more complicated systems using AFM-based single-molecule force spectroscopy. |
| 语种 | 英语 |
| WOS记录号 | WOS:000280861300031 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/71195]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zhang, Wenke |
| 作者单位 | 1.Jilin Univ, State Key Lab Supramol Struct & Mat, Coll Chem, Changchun 130012, Peoples R China 2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 3.Univ S Carolina, Dept Chem & Biochem, Columbia, SC 29208 USA 4.Univ S Carolina, NanoCtr, Columbia, SC 29208 USA 5.Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada |
| 推荐引用方式 GB/T 7714 | Liu, Ningning,Peng, Bo,Lin, Yuan,et al. Pulling Genetic RNA out of Tobacco Mosaic Virus Using Single-Molecule Force Spectroscopy[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2010,132(32):11036-11038. |
| APA | Liu, Ningning.,Peng, Bo.,Lin, Yuan.,Su, Zhaohui.,Niu, Zhongwei.,...&Shen, Jiacong.(2010).Pulling Genetic RNA out of Tobacco Mosaic Virus Using Single-Molecule Force Spectroscopy.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,132(32),11036-11038. |
| MLA | Liu, Ningning,et al."Pulling Genetic RNA out of Tobacco Mosaic Virus Using Single-Molecule Force Spectroscopy".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 132.32(2010):11036-11038. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。