Hyperbranched-Upon-Dendritic Macromolecules as Unimolecular Hosts for Controlled Release
文献类型：期刊论文
| 作者 | Xia, Changlei1; Ding, Xiangyu1; Sun, Yan1; Liu, Hewen1; Li, Yuesheng2 |
| 刊名 | JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
 |
| 出版日期 | 2010-09-15 |
| 卷号 | 48期号:18页码:4013-4019 |
| 关键词 | Core-shell Polymers Dendrimers Hyperbranched |
| ISSN号 | 0887-624X |
| DOI | 10.1002/pola.24185 |
| 英文摘要 | Novel amphiphilic hyperbranched-upon-dendritic polymers with a dendritic polyester core, a linear poly(epsilon-caprolactone) (PCL) inner shell, and a hyperbranched polyglycerol outer shell have been prepared The structures of the hyperbranched-upon-dendritic polymers were characterized by using NMR spectra The critical aggregating concentrations (CACs) of those amphiphtlic hyperbranched-upon-dendritic polymers were measured by using pyrene as the polarity probe To study the encapsulation performances of those hyperbranched-upon-dendritic polymers as unimolecular hosts, inter-molecular encapsulation was carefully prevented by controlling the host concentrations below their CACs and by washing with good organic solvents. The study on encapsulation of two model guest molecules, pyrene and indomethacin, was performed The amounts of encapsulated molecules were dependent mainly on the size of inner linear shells About three pyrene molecules or five indomethacin molecules were encapsulated in hyperbranched-upon-dendritic polymers with average PCL repeating units of two but different hyperbranched polyglycerol outer shells, whereas about five pyrene molecules or about 12 indomethacin molecules were encapsulated in those with PCL repeating units of nine The encapsulated molecules could be released in a controlled manner. Thus, the hyperbranched-upon-dendritic polymers could be used as unimolecular nanocarriers with controllable molecular encapsulation dosage for controlled release. (C) 2010 Wiley Periodicals, Inc J Polym Sci Part A. Polym Chem 48 4013-4019, 2010 |
| 语种 | 英语 |
| WOS记录号 | WOS:000281569500011 |
| 出版者 | JOHN WILEY & SONS INC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/71241]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Liu, Hewen |
| 作者单位 | 1.Univ Sci & Technol China, CAS Key Lab Soft Matter Chem, Dept Polymer Sci & Engn, Hefei 230026, Anhui, Peoples R China 2.State Key Lab Polymer Phys & Chem, Changchun 130022, Jilin, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xia, Changlei,Ding, Xiangyu,Sun, Yan,et al. Hyperbranched-Upon-Dendritic Macromolecules as Unimolecular Hosts for Controlled Release[J]. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY,2010,48(18):4013-4019. |
| APA | Xia, Changlei,Ding, Xiangyu,Sun, Yan,Liu, Hewen,&Li, Yuesheng.(2010).Hyperbranched-Upon-Dendritic Macromolecules as Unimolecular Hosts for Controlled Release.JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY,48(18),4013-4019. |
| MLA | Xia, Changlei,et al."Hyperbranched-Upon-Dendritic Macromolecules as Unimolecular Hosts for Controlled Release".JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY 48.18(2010):4013-4019. |
入库方式： OAI收割
来源：化学研究所
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