Synthesis of dendritic oligodeoxyribonucleotide analogs with nonionic diisopropylsilyl linkage
文献类型：期刊论文
| 作者 | Lv, Jin-Liang2; Zhao, Zhi-Yong2; Yang, Zhong-Qiang1; Liu, Dong-Sheng1; Fan, Qing-Hua2 |
| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2011-11-25 |
| 卷号 | 67期号:47页码:9080-9086 |
| 关键词 | Oligonucleotide Analogs Diisopropylsilyl Linkage Dendron Liquid-phase Synthesis Assembly |
| ISSN号 | 0040-4020 |
| DOI | 10.1016/j.tet.2011.09.108 |
| 英文摘要 | Series of new dendritic oligodeoxyribonucleotide analogs with diisopropylsilyl linkage were prepared via liquid-phase synthesis. Dendron was employed as soluble support, which facilitated purification of the products by simple solvent precipitation. Sequences leading to the dendritic octamer 5'-TSiTSiTSiTSiTSiT-(Si)T(Si)T(S)2-3' (T8D(2)) were prepared and each isolated intermediate was characterized by NMR and mass spectrometry. The recognition properties of two complementary dendritic dinucleotide analogs of TSiTSiD2 (T2D2) and A(Si)A(Si)D(2) (A2D(2)) were also studied by NMR and FT-MS spectra in a nonaqueous aprotic environment (C) 2011 Elsevier Ltd. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000296988800005 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/71479]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Liu, Dong-Sheng |
| 作者单位 | 1.Tsinghua Univ, Dept Chem, Key Lab Organ Optoelect & Mol Engn, Minist Educ, Beijing 100084, Peoples R China 2.Chinese Acad Sci, Inst Chem, CAS Key Lab Mol Recognit & Funct, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lv, Jin-Liang,Zhao, Zhi-Yong,Yang, Zhong-Qiang,et al. Synthesis of dendritic oligodeoxyribonucleotide analogs with nonionic diisopropylsilyl linkage[J]. TETRAHEDRON,2011,67(47):9080-9086. |
| APA | Lv, Jin-Liang,Zhao, Zhi-Yong,Yang, Zhong-Qiang,Liu, Dong-Sheng,&Fan, Qing-Hua.(2011).Synthesis of dendritic oligodeoxyribonucleotide analogs with nonionic diisopropylsilyl linkage.TETRAHEDRON,67(47),9080-9086. |
| MLA | Lv, Jin-Liang,et al."Synthesis of dendritic oligodeoxyribonucleotide analogs with nonionic diisopropylsilyl linkage".TETRAHEDRON 67.47(2011):9080-9086. |
入库方式： OAI收割
来源：化学研究所
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