High-sensitivity biosensors fabricated by tailoring the localized surface plasmon resonance property of core-shell gold nanorods
文献类型：期刊论文
| 作者 | Huang, Haowen1; Huang, Shaowen1; Yuan, Shishan2; Qu, Caiting1; Chen, Yi3; Xu, Zhongjian1; Liao, Bo1; Zeng, Yunlong1; Chu, Paul K.4 |
| 刊名 | ANALYTICA CHIMICA ACTA
 |
| 出版日期 | 2011-01-10 |
| 卷号 | 683期号:2页码:242-247 |
| 关键词 | Localized Surface Plasmon Resonance Gold Nanorod Composite Schistosomiasis Japonica Biosensor |
| ISSN号 | 0003-2670 |
| DOI | 10.1016/j.aca.2010.10.033 |
| 英文摘要 | An enhanced sensitive biosensor has been developed to detect biological targets by tailoring the localized surface plasmon resonance property of core-shell gold nanorods. In this new concept, a shell layer is produced on gold nanorods by generating a layer of chalcogenide on the gold nanorod surface after attachment of the recognition reagent, namely, goat IgG and antigen of schistosomiasis japonica. The bioactivity of these attached biomolecules is retained and the sensitivity of this biosensor is thus enhanced significantly. The plasmonic properties of the gold nanorods attached with the biomolecules can be adjusted and the plasmon resonance wavelength can be red-shifted up to several hundred nanometers in the visible or near infrared (NIR) region, which is extremely important to biosensing applications. This leads to a lager red-shift in the localized surface plasmon resonance absorption compared to the original gold nanorod-based sensor and hence offers greatly enhanced sensitivity in the detection of schistosomiasis japonica. The human serum infected with schistosomiasis japonica diluted to 1:50,000 (volume ratio, serum/buffer solution) can be detected readily. The technique offers enhanced sensitivity and can be easily extended to other sensing applications based on not only immuno-recognition but also other types of specific reactions. (C) 2010 Elsevier B.V. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000286854700013 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/71493]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Huang, Haowen |
| 作者单位 | 1.Hunan Univ Sci & Technol, Key Lab Theoret Chem & Mol Simulat, Minist Educ, Sch Chem & Chem Engn, Xiangtan 411201, Peoples R China 2.Hunan Normal Univ, Coll Med, Changsha 410013, Hunan, Peoples R China 3.Chinese Acad Sci, Key Lab Analyt Chem Living Biosyst, Inst Chem, Beijing 100190, Peoples R China 4.City Univ Hong Kong, Dept Phys & Mat Sci, Kowloon, Hong Kong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huang, Haowen,Huang, Shaowen,Yuan, Shishan,et al. High-sensitivity biosensors fabricated by tailoring the localized surface plasmon resonance property of core-shell gold nanorods[J]. ANALYTICA CHIMICA ACTA,2011,683(2):242-247. |
| APA | Huang, Haowen.,Huang, Shaowen.,Yuan, Shishan.,Qu, Caiting.,Chen, Yi.,...&Chu, Paul K..(2011).High-sensitivity biosensors fabricated by tailoring the localized surface plasmon resonance property of core-shell gold nanorods.ANALYTICA CHIMICA ACTA,683(2),242-247. |
| MLA | Huang, Haowen,et al."High-sensitivity biosensors fabricated by tailoring the localized surface plasmon resonance property of core-shell gold nanorods".ANALYTICA CHIMICA ACTA 683.2(2011):242-247. |
入库方式： OAI收割
来源：化学研究所
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