Research Progress of RNA Quadruplex
文献类型：期刊论文
| 作者 | Ji, Xiaohui1; Sun, Hongxia2; Zhou, Huaxi3; Xiang, Junfeng2; Tang, Yalin2; Zhao, Changqi1 |
| 刊名 | NUCLEIC ACID THERAPEUTICS
 |
| 出版日期 | 2011-06-01 |
| 卷号 | 21期号:3页码:185-200 |
| ISSN号 | 2159-3337 |
| DOI | 10.1089/nat.2010.0272 |
| 英文摘要 | RNA/DNA sequences rich in guanine (G) can form a 4-strand structure, G-quadruplex, which has been extensively researched and observed in mammalian, fungi, and plants, with in vivo existence in eukaryotic cells. Compared with DNA quadruplex, the potential existence of RNA quadruplex appears to be generally rare; however, it is believed by some researchers to be more inevitable in vivo and speculated to play an important role where it exists. Recently, researches concerning the function of G-quadruplexes in RNAs commence, making much progress. However, there is no available review particularly focusing on RNA quadruplex till now as we know. Therefore, we decide to give a review to comprehensively summarize research progress on it. This review highlights the diverse topologies for RNA quadruplex structure and its effect factors; outlines the current knowledge of RNA quadruplex's physiological functions in biological systems, especially in gene expression; and presents the prospects of RNA quadruplex. |
| 语种 | 英语 |
| WOS记录号 | WOS:000293654100010 |
| 出版者 | MARY ANN LIEBERT INC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/71853]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zhao, Changqi |
| 作者单位 | 1.Beijing Normal Univ, Key Lab Cell Proliferat & Regulat Biol, Beijing Key Lab Gene Engn Drugs & Biol Technol, Minist Educ,Coll Life Sci, Beijing 100875, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, State Key Lab Struct Chem Unstable & Stable Speci, Beijing 100080, Peoples R China 3.Beijing Normal Univ, Dept Syst Sci, Sch Management, Beijing 100875, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ji, Xiaohui,Sun, Hongxia,Zhou, Huaxi,et al. Research Progress of RNA Quadruplex[J]. NUCLEIC ACID THERAPEUTICS,2011,21(3):185-200. |
| APA | Ji, Xiaohui,Sun, Hongxia,Zhou, Huaxi,Xiang, Junfeng,Tang, Yalin,&Zhao, Changqi.(2011).Research Progress of RNA Quadruplex.NUCLEIC ACID THERAPEUTICS,21(3),185-200. |
| MLA | Ji, Xiaohui,et al."Research Progress of RNA Quadruplex".NUCLEIC ACID THERAPEUTICS 21.3(2011):185-200. |
入库方式： OAI收割
来源：化学研究所
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