PH-responsive nano-assemblies of amino poly(glycerol methacrylate)
文献类型：期刊论文
| 作者 | Gao Hui1; Ma Yanan1; Lu Xueyou1; Liang Yongri2; Chen Baoquan1; Ma Jianbiao1,3 |
| 刊名 | EUROPEAN POLYMER JOURNAL
 |
| 出版日期 | 2011-06-01 |
| 卷号 | 47期号:6页码:1232-1239 |
| 关键词 | Ph-sensitive Nanoparticles Amino Polymer Poly(Glycidyl Methacrylate) Congo Red |
| ISSN号 | 0014-3057 |
| DOI | 10.1016/j.eurpolymj.2011.03.009 |
| 英文摘要 | Both linear and star-shaped poly(glycidyl methacrylate) (PGMA) polymers were modified with different amines and used to prepare pH-sensitive nano-assemblies. Nanoprecipitation technique and dialysis method were used to prepare the polymeric nanoparticles. These nano-assemblies showed pH-sensitive disassociation properties under an acidic condition. The polymers were quite effective in encapsulation of Congo red (CR). Atom force microscopy images showed that the nanoparticles prepared using nanoprecipitation technique are spherical before and after encapsulation of CR. The disassociation pH, encapsulation efficiency, loading capacity and release properties of these polymers were found to depend on their backbone architecture and the amine type. By adjusting of these factors, such type of polymers hold promise as an interesting drug delivery vehicle. (C) 2011 Elsevier Ltd. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000291523600002 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/72021]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Gao Hui |
| 作者单位 | 1.Tianjin Univ Technol, Sch Chem & Chem Engn, Tianjin 300384, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China 3.Nankai Univ, Inst Polymer Chem, Minist Educ, Key Lab Funct Polymer Mat, Tianjin 300071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao Hui,Ma Yanan,Lu Xueyou,et al. PH-responsive nano-assemblies of amino poly(glycerol methacrylate)[J]. EUROPEAN POLYMER JOURNAL,2011,47(6):1232-1239. |
| APA | Gao Hui,Ma Yanan,Lu Xueyou,Liang Yongri,Chen Baoquan,&Ma Jianbiao.(2011).PH-responsive nano-assemblies of amino poly(glycerol methacrylate).EUROPEAN POLYMER JOURNAL,47(6),1232-1239. |
| MLA | Gao Hui,et al."PH-responsive nano-assemblies of amino poly(glycerol methacrylate)".EUROPEAN POLYMER JOURNAL 47.6(2011):1232-1239. |
入库方式： OAI收割
来源：化学研究所
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