Programmable DNA switch for bioresponsive controlled release
文献类型：期刊论文
| 作者 | Chen, Linfeng1; Wen, Yongqiang1; Su, Bin1; Di, Jiancheng2; Song, Yanlin1; Jiang, Lei1 |
| 刊名 | JOURNAL OF MATERIALS CHEMISTRY
 |
| 出版日期 | 2011 |
| 卷号 | 21期号:36页码:13811-13816 |
| ISSN号 | 0959-9428 |
| DOI | 10.1039/c1jm12203g |
| 英文摘要 | A bioresponsive controlled release system based on mesoporous silica nanoparticles (MS) was designed and constructed. Through the DNAa/DANb assembly, DNAb-modified gold nanoparticles (AuNPs-DNAb) could be attached to the pores of MS covalently functionalized with DNAa. In the presence of adenosine, the pores of MS could be opened and the encapsulated guest was released, due to the interaction between DNAb and adenosine. Forster resonance energy transfer (FRET) was used to confirm the switching mechanism. Furthermore, the carry system was exclusively responsive to adenosine, and the process was dependent on the concentration of adenosine, which made the system promising for target-directing controlled release. |
| 语种 | 英语 |
| WOS记录号 | WOS:000294441300014 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/72845]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wen, Yongqiang |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, New Mat Lab, Key Lab Organ Solids,BNLMS, Beijing 100190, Peoples R China 2.Jilin Univ, Coll Chem, State Key Lab Inorgan Synth & Preparat Chem, Changchun 130012, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Linfeng,Wen, Yongqiang,Su, Bin,et al. Programmable DNA switch for bioresponsive controlled release[J]. JOURNAL OF MATERIALS CHEMISTRY,2011,21(36):13811-13816. |
| APA | Chen, Linfeng,Wen, Yongqiang,Su, Bin,Di, Jiancheng,Song, Yanlin,&Jiang, Lei.(2011).Programmable DNA switch for bioresponsive controlled release.JOURNAL OF MATERIALS CHEMISTRY,21(36),13811-13816. |
| MLA | Chen, Linfeng,et al."Programmable DNA switch for bioresponsive controlled release".JOURNAL OF MATERIALS CHEMISTRY 21.36(2011):13811-13816. |
入库方式： OAI收割
来源：化学研究所
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