Chiral Primary Amine Catalyzed Asymmetric Direct Cross-Aldol Reaction of Acetaldehyde
文献类型：期刊论文
| 作者 | Hu, Shenshen; Zhang, Long; Li, Jiuyuan; Luo, Sanzhong; Cheng, Jin-Pei |
| 刊名 | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
 |
| 出版日期 | 2011-06-01 |
| 期号 | 18页码:3347-3352 |
| 关键词 | Aldehydes Aldol Reactions Amines Asymmetric Catalysis Organocatalysis |
| ISSN号 | 1434-193X |
| DOI | 10.1002/ejoc.201100267 |
| 英文摘要 | The first primary aminocatalytic direct cross-aldol reaction of acetaldehyde is presented. Among the various vicinal diamines screened, the L-tert-leucine derivative 1c in conjunction with (H4SiW12O40)(0.25) was identified as the optimal catalyst; good catalytic activity (up to 99% yield in 4 h), and high enantioselectivities (up to 92% ee) were achieved for a range of donors, including aromatic aldehydes and isatin derivatives. Aqueous acetaldehyde solution and paraldehyde can be conveniently applied in this system. |
| 语种 | 英语 |
| WOS记录号 | WOS:000291583700010 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/73363]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Luo, Sanzhong |
| 作者单位 | Chinese Acad Sci, BNLMS, CAS Key Lab Mol Recognit & Funct, Inst Chem, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hu, Shenshen,Zhang, Long,Li, Jiuyuan,et al. Chiral Primary Amine Catalyzed Asymmetric Direct Cross-Aldol Reaction of Acetaldehyde[J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,2011(18):3347-3352. |
| APA | Hu, Shenshen,Zhang, Long,Li, Jiuyuan,Luo, Sanzhong,&Cheng, Jin-Pei.(2011).Chiral Primary Amine Catalyzed Asymmetric Direct Cross-Aldol Reaction of Acetaldehyde.EUROPEAN JOURNAL OF ORGANIC CHEMISTRY(18),3347-3352. |
| MLA | Hu, Shenshen,et al."Chiral Primary Amine Catalyzed Asymmetric Direct Cross-Aldol Reaction of Acetaldehyde".EUROPEAN JOURNAL OF ORGANIC CHEMISTRY .18(2011):3347-3352. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。