Preparation of Micro-/Nano- Nonspherical Polymer Particles
文献类型:期刊论文
作者 | Li Hongfu1,2; Zhang Homing1; Guo Xinglin2 |
刊名 | PROGRESS IN CHEMISTRY
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出版日期 | 2011-06-01 |
卷号 | 23期号:6页码:1196-1210 |
关键词 | Micro- Nano- Nonspherical Polymer Particles |
ISSN号 | 1005-281X |
英文摘要 | Precisely shaped polymer particles are widely used for various applications, especially in the design of new carriers for drug delivery, micro- or nano- nonspherical polymer particles exhibit more obvious advantages to their corresponding spherical particles, such as in the drug release, in vivo transportation, circulation, targeting ability, the swallow speed by the cells, and the adhesion behavior on vascular wall. If we can prepare the nonspherical particles with specific shape for the drug carriers, it will greatly enhance in vivo therapy efficiency. But in the particle research field, until now, spherical system research is in the dominate position, so it's necessary to summarize the preparation methods of the micro- or nano- nonspherical polymer particles. In this review, 14 preparation methods (microfluidics, stretching of spherical particles, porous silica, template and particles self-assembly, particle replication in nonwetting templates, reactive ion etching, electrospray, ion beam irradiation, controlled phase separation in seeded polymerization, miniemulsion polymerization, local surface modification at the Interface, amphiphilic macromolecule self-assembly, oil-in-water emulsion solvent evaporation technique, Y-shape surfactant) as well as their advantages and disadvantages of micro- or nano- nonspherical polymer particles are introduced in detail. These methods could be joined up to prepare more complex shapes. |
语种 | 英语 |
WOS记录号 | WOS:000292342500016 |
出版者 | CHINESE ACAD SCIENCES |
源URL | [http://ir.iccas.ac.cn/handle/121111/73955] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Li Hongfu |
作者单位 | 1.Beihang Univ, Sch Mat Sci & Engn, Beijing 100191, Peoples R China 2.Chinese Acad Sci, State Key Lab Polymer Phys & Chem, Inst Chem, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Li Hongfu,Zhang Homing,Guo Xinglin. Preparation of Micro-/Nano- Nonspherical Polymer Particles[J]. PROGRESS IN CHEMISTRY,2011,23(6):1196-1210. |
APA | Li Hongfu,Zhang Homing,&Guo Xinglin.(2011).Preparation of Micro-/Nano- Nonspherical Polymer Particles.PROGRESS IN CHEMISTRY,23(6),1196-1210. |
MLA | Li Hongfu,et al."Preparation of Micro-/Nano- Nonspherical Polymer Particles".PROGRESS IN CHEMISTRY 23.6(2011):1196-1210. |
入库方式: OAI收割
来源:化学研究所
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