中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Preparation of Micro-/Nano- Nonspherical Polymer Particles

文献类型:期刊论文

作者Li Hongfu1,2; Zhang Homing1; Guo Xinglin2
刊名PROGRESS IN CHEMISTRY
出版日期2011-06-01
卷号23期号:6页码:1196-1210
关键词Micro- Nano- Nonspherical Polymer Particles
ISSN号1005-281X
英文摘要Precisely shaped polymer particles are widely used for various applications, especially in the design of new carriers for drug delivery, micro- or nano- nonspherical polymer particles exhibit more obvious advantages to their corresponding spherical particles, such as in the drug release, in vivo transportation, circulation, targeting ability, the swallow speed by the cells, and the adhesion behavior on vascular wall. If we can prepare the nonspherical particles with specific shape for the drug carriers, it will greatly enhance in vivo therapy efficiency. But in the particle research field, until now, spherical system research is in the dominate position, so it's necessary to summarize the preparation methods of the micro- or nano- nonspherical polymer particles. In this review, 14 preparation methods (microfluidics, stretching of spherical particles, porous silica, template and particles self-assembly, particle replication in nonwetting templates, reactive ion etching, electrospray, ion beam irradiation, controlled phase separation in seeded polymerization, miniemulsion polymerization, local surface modification at the Interface, amphiphilic macromolecule self-assembly, oil-in-water emulsion solvent evaporation technique, Y-shape surfactant) as well as their advantages and disadvantages of micro- or nano- nonspherical polymer particles are introduced in detail. These methods could be joined up to prepare more complex shapes.
语种英语
WOS记录号WOS:000292342500016
出版者CHINESE ACAD SCIENCES
源URL[http://ir.iccas.ac.cn/handle/121111/73955]  
专题中国科学院化学研究所
通讯作者Li Hongfu
作者单位1.Beihang Univ, Sch Mat Sci & Engn, Beijing 100191, Peoples R China
2.Chinese Acad Sci, State Key Lab Polymer Phys & Chem, Inst Chem, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714
Li Hongfu,Zhang Homing,Guo Xinglin. Preparation of Micro-/Nano- Nonspherical Polymer Particles[J]. PROGRESS IN CHEMISTRY,2011,23(6):1196-1210.
APA Li Hongfu,Zhang Homing,&Guo Xinglin.(2011).Preparation of Micro-/Nano- Nonspherical Polymer Particles.PROGRESS IN CHEMISTRY,23(6),1196-1210.
MLA Li Hongfu,et al."Preparation of Micro-/Nano- Nonspherical Polymer Particles".PROGRESS IN CHEMISTRY 23.6(2011):1196-1210.

入库方式: OAI收割

来源:化学研究所

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