Effect of selective substitution of 5-bromocytosine on conformation of DNA triple helices
文献类型：期刊论文
| 作者 | Liu, MZ; Yang, LJ; Deng, WL; Su, M; Wang, C; Lin, SB; Kan, LS; Bai, CL |
| 刊名 | JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
 |
| 出版日期 | 1998-04-01 |
| 卷号 | 15期号:5页码:895-903 |
| ISSN号 | 0739-1102 |
| 英文摘要 | Three tripler DNAs containing 5-bromocytosine[C-Br] were studied by vibrational spectroscopy and molecular modelling. Firstly, three oligodeoxypyrimidines of 5'-(TC)3-T4-((CT)-C-Br)3 [(CC)-C-Br], 5'-((TC)-C-Br)3-T4-(CT)3 [(CC)-C-Br] and 5'-((TC)-C-Br)3-T4-((CT)-C-Br)3 [(CC)-C-Br-C-Br] were synthesized and then reacted with an oligodeoxypurine of 5'-(AG)(3) at pH=4.5 in phosphate buffer respectively to form three comparative hairpin tripler named CY,YC and YY. The results of FT-Raman and IR revealed that YY is almost in A-like form, CY and YC are combinations of A-like form and B-like form, but A-form dominates in CY while B-form is equivalent as A-form in YC. The result is consistent with the theoretical analysis. |
| 语种 | 英语 |
| WOS记录号 | WOS:000073642200007 |
| 出版者 | ADENINE PRESS INC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/74547]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Kan, LS |
| 作者单位 | 1.Acad Sinica, Inst Chem, Taipei, Taiwan 2.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, MZ,Yang, LJ,Deng, WL,et al. Effect of selective substitution of 5-bromocytosine on conformation of DNA triple helices[J]. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS,1998,15(5):895-903. |
| APA | Liu, MZ.,Yang, LJ.,Deng, WL.,Su, M.,Wang, C.,...&Bai, CL.(1998).Effect of selective substitution of 5-bromocytosine on conformation of DNA triple helices.JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS,15(5),895-903. |
| MLA | Liu, MZ,et al."Effect of selective substitution of 5-bromocytosine on conformation of DNA triple helices".JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS 15.5(1998):895-903. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。