Direct visualization of DNA decondensation on mica by atomic force microscopy
文献类型：期刊论文
| 作者 | Sun, XG; Cao, EH; Liu, MZ; Bai, CL |
| 刊名 | CHEMISTRY LETTERS
 |
| 出版日期 | 1999-09-01 |
| 期号 | 9页码:981-982 |
| ISSN号 | 0366-7022 |
| 英文摘要 | Lambda DNA/Hind III solution in the presence of cations was gradually diluted into four different concentration, namely 50, 25, 10, 1 ng/mu l. The morphology change during this process was observed by atomic force microscopy. Images reveal that at the highest concentration, a flower-like structure with multiple loops crossing at the same point was exhibited on mice. Following it are some irregularly planer "layers" accompanied by occasional toroids. When DNA concentration was diluted to 10 ng/mu l, a large complex network structure appeared, which was eventually replaced by the extended and isolated DNA molecules at 1 ng/mu l. This structural transition may be helpful for us to understand the molecular mechanism of DNA decondensation. |
| 语种 | 英语 |
| WOS记录号 | WOS:000082760900066 |
| 出版者 | CHEMICAL SOC JAPAN |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/74967]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Cao, EH |
| 作者单位 | 1.Chinese Acad Sci, Inst Biophys, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, XG,Cao, EH,Liu, MZ,et al. Direct visualization of DNA decondensation on mica by atomic force microscopy[J]. CHEMISTRY LETTERS,1999(9):981-982. |
| APA | Sun, XG,Cao, EH,Liu, MZ,&Bai, CL.(1999).Direct visualization of DNA decondensation on mica by atomic force microscopy.CHEMISTRY LETTERS(9),981-982. |
| MLA | Sun, XG,et al."Direct visualization of DNA decondensation on mica by atomic force microscopy".CHEMISTRY LETTERS .9(1999):981-982. |
入库方式： OAI收割
来源：化学研究所
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