Preliminary study of oral polylactide microcapsulated insulin in vitro and in vivo
文献类型：期刊论文
| 作者 | Ma, XY; Pan, GM; Lu, Z; Hu, JS; Bei, JZ; Jia, JH; Wang, SG |
| 刊名 | DIABETES OBESITY & METABOLISM
 |
| 出版日期 | 2000-07-01 |
| 卷号 | 2期号:4页码:243-250 |
| 关键词 | Diabetes Oral Insulin Microcapsulation Polylactide |
| ISSN号 | 1462-8902 |
| 英文摘要 | Aim: Although the oral route for insulin delivery is the most convenient, directly administered oral insulin is degraded by proteolytic enzymes in the gastrointestinal (GI) tract. Polylactide was prepared in order to microcapsulate the insulin to avoid the enzymes in the GI. The physical characteristics and therapeutic possibilities of polylactide microcapsulated insulin (PLA-MCI) were studied in vivo and in vitro. |
| 语种 | 英语 |
| WOS记录号 | WOS:000088302800006 |
| 出版者 | BLACKWELL SCIENCE LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/75883]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Ma, XY |
| 作者单位 | 1.Beijing 304 Hosp PLA, Dept Endocrinol, Beijing 1000037, Peoples R China 2.Chinese Acad Sci, Inst Chem, PCLCC, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ma, XY,Pan, GM,Lu, Z,et al. Preliminary study of oral polylactide microcapsulated insulin in vitro and in vivo[J]. DIABETES OBESITY & METABOLISM,2000,2(4):243-250. |
| APA | Ma, XY.,Pan, GM.,Lu, Z.,Hu, JS.,Bei, JZ.,...&Wang, SG.(2000).Preliminary study of oral polylactide microcapsulated insulin in vitro and in vivo.DIABETES OBESITY & METABOLISM,2(4),243-250. |
| MLA | Ma, XY,et al."Preliminary study of oral polylactide microcapsulated insulin in vitro and in vivo".DIABETES OBESITY & METABOLISM 2.4(2000):243-250. |
入库方式： OAI收割
来源：化学研究所
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