"Protein-only" or "virino" in prion diseases?
文献类型：期刊论文
| 作者 | Yang, CM; Chen, Y |
| 刊名 | CHINESE SCIENCE BULLETIN
 |
| 出版日期 | 2000-02-01 |
| 卷号 | 45期号:3页码:285-288 |
| 关键词 | Prions Mad Cow Disease Neurodegenerative Disorder Subviral Pathogen Prion Radical |
| ISSN号 | 1001-6538 |
| 英文摘要 | 60-year prion and scrapie research has led to a dilemma in understanding the unknown aetiology of the infectious neurodegenerative disorders with intriguing features. Current progress and dilemma in prion research are briefly but critically reviewed. Instead of providing a comprehensive coverage of the research history, attentions in this view are drawn toward both the major breakthrough in the advancement of protein-only hypothesis, and the puzzle why this hypothesis has not been fully accepted. In order to resolve the prion enigma in neuroscience, it is suggested that both technical and concept barriers remain to be crossed. Since prion research is a multi-interdisciplinary subject, this view is intended to both facilitate a better understanding of prion phenomenon by more scientists in natural science, and invite scientists outside the fields of molecular genetics and protein science for collaboration. |
| 语种 | 英语 |
| WOS记录号 | WOS:000085980500022 |
| 出版者 | SCIENCE PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/75953]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Yang, CM |
| 作者单位 | 1.Univ Calif San Diego, Inst Life Sci & Hlth, La Jolla, CA 92093 USA 2.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, CM,Chen, Y. "Protein-only" or "virino" in prion diseases?[J]. CHINESE SCIENCE BULLETIN,2000,45(3):285-288. |
| APA | Yang, CM,&Chen, Y.(2000)."Protein-only" or "virino" in prion diseases?.CHINESE SCIENCE BULLETIN,45(3),285-288. |
| MLA | Yang, CM,et al.""Protein-only" or "virino" in prion diseases?".CHINESE SCIENCE BULLETIN 45.3(2000):285-288. |
入库方式： OAI收割
来源：化学研究所
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