中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Study on colloidal Au-enhanced DNA sensing by quartz crystal microbalance

文献类型:期刊论文

作者Lin, L; Zhao, HQ; Li, JR; Tang, JA; Duan, MX; Jiang, L
刊名BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
出版日期2000-08-11
卷号274期号:3页码:817-820
关键词Colloidal Au Dna Sensing Quartz Crystal Microbalance
ISSN号0006-291X
英文摘要Colloidal Au is reported for enhancement the immobilization capacity and ultimately detection limit of DNA using quartz crystal microbalance (QCM). Immobilization of similar to 12 nm-diameter colloidal Au on to an An-coated QCM resulted in an easier attachment of oligonucleotide, with a mercaptohexyl group at the 5'-phosphate end and an increased capacity for nucleic acid detection, DNA immobilization and hybridization was monitored from QCM frequency changes, Hybridization was induced by exposure of the DNA-containing films to complementary DNA in solution, A much higher sensitivity was obtained for the analyte. The Au nanoparticle films on the Au plate provide a novel means for the fabrication of DNA sensor, (C) 2000 Academic Press.
语种英语
WOS记录号WOS:000088817800041
出版者ACADEMIC PRESS INC
源URL[http://ir.iccas.ac.cn/handle/121111/76293]  
专题中国科学院化学研究所
通讯作者Lin, L
作者单位1.Chinese Acad Sci, Inst Chem, Colloid & Interface Lab, Mol Ctr, Beijing 100080, Peoples R China
2.Tsing Hua Univ, Fac Biotechnol & Bioengn, Hsinchu, Taiwan
推荐引用方式
GB/T 7714
Lin, L,Zhao, HQ,Li, JR,et al. Study on colloidal Au-enhanced DNA sensing by quartz crystal microbalance[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2000,274(3):817-820.
APA Lin, L,Zhao, HQ,Li, JR,Tang, JA,Duan, MX,&Jiang, L.(2000).Study on colloidal Au-enhanced DNA sensing by quartz crystal microbalance.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,274(3),817-820.
MLA Lin, L,et al."Study on colloidal Au-enhanced DNA sensing by quartz crystal microbalance".BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 274.3(2000):817-820.

入库方式: OAI收割

来源:化学研究所

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