Capillary electrophoresis of neurotransmitters under the control of radial electric field
文献类型：期刊论文
| 作者 | Zhu, Y; Chen, Y |
| 刊名 | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2001-06-01 |
| 卷号 | 29期号:6页码:661-663 |
| 关键词 | Capillary Electrophoresis Neurotransmitter Separation Radial Electric Field Control |
| ISSN号 | 0253-3820 |
| 英文摘要 | Separations of neurotransmitters such as dopamine (DA), serotonin (5-HA), norepinephrine (NE) and epinephrine (E) were performed successfully using a homemade electric field modulated capillary electrophoretic system, which could offer both radial and axial electric fields with only one high voltage power supply. DA and 5-HT were eluted simulaneously and could not be resolved in 0.01 mol/L phosphate buffer at pH 2.5. Alcohol additives, such as methanol, ethanol or l-propanol were added to the buffer to change the solvation shell of the solutes, which changed their effective sizes and electrophoretic mobilities of the solutes accordingly. The optimum composition was a buffer of 20% ( V/V) 1-propanol, with resulted resolutions 0.74 (DA/5-HT), 0.56(5-HT/NE) and 0.77 (NE/E). If a positive radial voltage of 6.6 kV was applied, the resolutions were improved to 1.48, 0.71 and 1.32, respectively. |
| 语种 | 英语 |
| WOS记录号 | WOS:000169539000011 |
| 出版者 | FENXI HUAXUE |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/76855]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zhu, Y |
| 作者单位 | 1.Chinese Acad Prevent Med, Inst Environm Hlth Monitoring, Beijing 100021, Peoples R China 2.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Y,Chen, Y. Capillary electrophoresis of neurotransmitters under the control of radial electric field[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2001,29(6):661-663. |
| APA | Zhu, Y,&Chen, Y.(2001).Capillary electrophoresis of neurotransmitters under the control of radial electric field.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,29(6),661-663. |
| MLA | Zhu, Y,et al."Capillary electrophoresis of neurotransmitters under the control of radial electric field".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 29.6(2001):661-663. |
入库方式： OAI收割
来源：化学研究所
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