Biodegradation behaviour of poly(lactide-co-glycolide) induced by microorganisms
文献类型:期刊论文
作者 | Cai, Q; Bei, JZ; Luo, AQ; Wang, SG |
刊名 | POLYMER DEGRADATION AND STABILITY
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出版日期 | 2001 |
卷号 | 71期号:2页码:243-251 |
关键词 | Poly(Lactide-co-glycolide) Biodegradation Micro Organism Fungi |
ISSN号 | 0141-3910 |
英文摘要 | The effect of microorganisms on degradation of PLLA was compared by using different kind of fungus in vitro. Fusarium L023 showed the strongest activity in accelerating the degradation of PLLA. Therefore, the in vitro degradation of PLGA copolymers was examined by immersing PLGA(50/50) and PLGA(70/30) films in media with or without Fusarium L023. Degradation of the polymeric films was monitored by measuring inherent viscosity and weight loss, as well as using techniques such as GPC, H-1 NMR, DSC and SEM. In this case, the degradation of PLGA copolymers could be markedly accelerated by Fusarium L023. The microorganism assimilated the released oligomers as carbon-source, and this could explain why the inherent viscosity decreased more slowly for inoculated samples at the later stage than those in the controlled medium. Moreover, the Fusarium L023 would favor the degradation of PLGA copolymers by destroying the crystallization of PLLA segments at the later stage, which was caused by the preferential loss of glycotyl unit in the case of hydrolysis, for Fusarium L023 was more effective on accelerating the degradation of PLLA than PGA. (C) 2001 Elsevier Science Ltd. All rights reserved. |
语种 | 英语 |
WOS记录号 | WOS:000166656400006 |
出版者 | ELSEVIER SCI LTD |
源URL | [http://ir.iccas.ac.cn/handle/121111/77105] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Wang, SG |
作者单位 | 1.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Inst Microbiol, State Key Lab Microbial Resources, Beijing 100080, Peoples R China |
推荐引用方式 GB/T 7714 | Cai, Q,Bei, JZ,Luo, AQ,et al. Biodegradation behaviour of poly(lactide-co-glycolide) induced by microorganisms[J]. POLYMER DEGRADATION AND STABILITY,2001,71(2):243-251. |
APA | Cai, Q,Bei, JZ,Luo, AQ,&Wang, SG.(2001).Biodegradation behaviour of poly(lactide-co-glycolide) induced by microorganisms.POLYMER DEGRADATION AND STABILITY,71(2),243-251. |
MLA | Cai, Q,et al."Biodegradation behaviour of poly(lactide-co-glycolide) induced by microorganisms".POLYMER DEGRADATION AND STABILITY 71.2(2001):243-251. |
入库方式: OAI收割
来源:化学研究所
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