Solution conformation study on a beta-turn forming peptide
文献类型：期刊论文
| 作者 | Gao, F; Sha, YL; Qiu, Y; Wang, YF; Li, YL; Lai, LH; Wu, HM |
| 刊名 | ACTA PHYSICO-CHIMICA SINICA
 |
| 出版日期 | 2001-07-01 |
| 卷号 | 17期号:7页码:619-621 |
| 关键词 | Beta-turn Cd Ft-ir Nmr Peptide |
| ISSN号 | 1000-6818 |
| DOI | 10.3866/PKU.WHXB20010709 |
| 英文摘要 | The model six-residue linear peptide AAGDYY-NH2 from TEM-1 beta -lactamase inhibitor protein and BLIP was predicted to adopt a beta -turn conformation and synthesized in order to elucidate the mechanism of beta -turn formation and stability. Its structural preferences in solution were comprehensively characterized using CD (circular dichroism), FT-IR and H-1-NMR spectroscopy. The set of observed short- and medium-range NOEs, the restrained molecular dynamics simulation, CD and FT-IR spectroscopy were consistent with the formation of beta -turn in solution by the model peptide. The results implicate beta -turn playing an important role in the process of protein folding. |
| 语种 | 英语 |
| WOS记录号 | WOS:000170070000009 |
| 出版者 | PEKING UNIV PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/77205]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Sha, YL |
| 作者单位 | 1.Peking Univ, Coll Chem & Mol Engn, Inst Phys Chem, State Key Lab Struct Chem Unstable & Stable Speci, Beijing 100871, Peoples R China 2.Peking Univ, Sch Basic Med Sci, Dept Biophys, Beijing 100083, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao, F,Sha, YL,Qiu, Y,et al. Solution conformation study on a beta-turn forming peptide[J]. ACTA PHYSICO-CHIMICA SINICA,2001,17(7):619-621. |
| APA | Gao, F.,Sha, YL.,Qiu, Y.,Wang, YF.,Li, YL.,...&Wu, HM.(2001).Solution conformation study on a beta-turn forming peptide.ACTA PHYSICO-CHIMICA SINICA,17(7),619-621. |
| MLA | Gao, F,et al."Solution conformation study on a beta-turn forming peptide".ACTA PHYSICO-CHIMICA SINICA 17.7(2001):619-621. |
入库方式： OAI收割
来源：化学研究所
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