High performance affinity chromatography of antithrombin III based on monodisperse poly (glycidyl methacrylate) beads
文献类型：期刊论文
| 作者 | Zhao, YX; Shangguan, DH; Zhao, R; Shu, TS; Liu, GQ |
| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2001-05-01 |
| 卷号 | 12期号:5页码:443-446 |
| 关键词 | High Performance Affinity Chromatography Antithrombin Iii Heparin |
| ISSN号 | 1001-8417 |
| 英文摘要 | A new approach for the separation of antithrombin III with high performance affinity chromatography (HPAC) was described. A novel monodisperse, non-porous, cross-linked poly (glycidyl methacrylate) beads (PGMA) were used as the affinity support. With the water-soluble carbodiimide, heparin was linked covalently to amino-PGMA-beads, which was prepared by amination of PGMA. The adsorbent obtained exhibits high binding activity to antithrombin III (ATIII), good resolution and excellent mechanical properties and can be used under high flow rate. |
| 语种 | 英语 |
| WOS记录号 | WOS:000168994500023 |
| 出版者 | CHINESE CHEMICAL SOCIETY |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/77243]  |
| 专题 | 中国科学院化学研究所 |
| 作者单位 | Chinese Acad Sci, Ctr Mol Sci, Inst Chem, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, YX,Shangguan, DH,Zhao, R,et al. High performance affinity chromatography of antithrombin III based on monodisperse poly (glycidyl methacrylate) beads[J]. CHINESE CHEMICAL LETTERS,2001,12(5):443-446. |
| APA | Zhao, YX,Shangguan, DH,Zhao, R,Shu, TS,&Liu, GQ.(2001).High performance affinity chromatography of antithrombin III based on monodisperse poly (glycidyl methacrylate) beads.CHINESE CHEMICAL LETTERS,12(5),443-446. |
| MLA | Zhao, YX,et al."High performance affinity chromatography of antithrombin III based on monodisperse poly (glycidyl methacrylate) beads".CHINESE CHEMICAL LETTERS 12.5(2001):443-446. |
入库方式： OAI收割
来源：化学研究所
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