Study on the degeneracy of antisense peptides using affinity chromatography
文献类型：期刊论文
| 作者 | Zhao, R; Yu, X; Liu, H; Zhai, LL; Xiong, SX; Su, TS; Liu, GQ |
| 刊名 | JOURNAL OF CHROMATOGRAPHY A
 |
| 出版日期 | 2001-04-13 |
| 卷号 | 913期号:1-2页码:421-428 |
| 关键词 | Affinity Chromotography Immobilized Peptides Degeneracy Antisense Peptides Peptides Amino Acids |
| ISSN号 | 0021-9673 |
| 英文摘要 | The degeneracy of antisense peptides was studied by high-performance affinity chromatography. A model sense peptide (AAAA) and its antisense peptides (CGGG, GGGG, RGGG, SGGG) were designed and synthesized according to the degeneracy of genetic codes. An affinity column with AAAA as the Ligand was prepared. The affinity chromatographic behaviors of antisense peptides on the column were evaluated. The results indicated that model antisense peptides have clear retention on the immobilized AAAA affinity column. RGGG showed the strongest affinity interaction. Similar result was obtained from another experiment that Arg-substituted antisense peptide of fusion peptide (1-11) of influenza virus A was also shown the highest affinity binding to immobilized fusion peptide. (C) 2001 Elsevier Science B.V. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000168156100043 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/77421]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Liu, GQ |
| 作者单位 | Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, R,Yu, X,Liu, H,et al. Study on the degeneracy of antisense peptides using affinity chromatography[J]. JOURNAL OF CHROMATOGRAPHY A,2001,913(1-2):421-428. |
| APA | Zhao, R.,Yu, X.,Liu, H.,Zhai, LL.,Xiong, SX.,...&Liu, GQ.(2001).Study on the degeneracy of antisense peptides using affinity chromatography.JOURNAL OF CHROMATOGRAPHY A,913(1-2),421-428. |
| MLA | Zhao, R,et al."Study on the degeneracy of antisense peptides using affinity chromatography".JOURNAL OF CHROMATOGRAPHY A 913.1-2(2001):421-428. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。