Enhancement of the immobilization and discrimination of DNA probe on a biosensor using gold nanoparticles
文献类型：期刊论文
| 作者 | Zhao, HQ; Lin, L; Tang, J; Duan, MX; Jiang, L |
| 刊名 | CHINESE SCIENCE BULLETIN
 |
| 出版日期 | 2001-07-01 |
| 卷号 | 46期号:13页码:1074-1077 |
| ISSN号 | 1001-6538 |
| 关键词 | Au Nanoparticles Dna Sensor Quartz Crystal Microbalance |
| 英文摘要 | Nanoparticles have been widely utilized in bio. logical research in recent years. 1,6-Hexanedithiol was used as the medium in this work to attach An nanoparticles on the gold plates. We studied the immobilization and hybridization of DNA probes onto the resulted plates using the quartz crystal microbalance method. Approximately 3-5 times adsorption enhancement of HS-DNA on the plates was obtained under our experimental conditions. Using this DNA sensor, the sensitivity was promoted by approximately three times to 0.35 mug/mL. |
| 语种 | 英语 |
| 出版者 | SCIENCE PRESS |
| WOS记录号 | WOS:000170251400005 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/77685]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Jiang, L |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Lab Colloid & Interface Sci, Beijing 100080, Peoples R China 2.Tsing Hua Univ, Dept Biol Sci & Botechnol, Beijing 100084, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, HQ,Lin, L,Tang, J,et al. Enhancement of the immobilization and discrimination of DNA probe on a biosensor using gold nanoparticles[J]. CHINESE SCIENCE BULLETIN,2001,46(13):1074-1077. |
| APA | Zhao, HQ,Lin, L,Tang, J,Duan, MX,&Jiang, L.(2001).Enhancement of the immobilization and discrimination of DNA probe on a biosensor using gold nanoparticles.CHINESE SCIENCE BULLETIN,46(13),1074-1077. |
| MLA | Zhao, HQ,et al."Enhancement of the immobilization and discrimination of DNA probe on a biosensor using gold nanoparticles".CHINESE SCIENCE BULLETIN 46.13(2001):1074-1077. |
入库方式： OAI收割
来源：化学研究所
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