Two-photon excitation studies of hypocrellins for photodynamic therapy
文献类型：期刊论文
| 作者 | Liu, J; Zhao, YW; Zhao, JQ; Xia, AD; Jiang, LJ; Wu, S; Ma, L; Dong, YQ |
| 刊名 | JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
 |
| 出版日期 | 2002-11-01 |
| 卷号 | 68期号:2-3页码:156-164 |
| 关键词 | Hypocrellins Photosensitization Two-photon Phototherapy Dynamics (Tppdt) Two-photon Cross Section Hela Cell |
| ISSN号 | 1011-1344 |
| 英文摘要 | The photophysical and photochemical properties of hypocrellins (HA and HB) are examined with two-photon excitations at 800 nm using femtosecond pulses from a Ti:sapphire laser. The two-photon excited fluorescence spectra of HA and HB are very similar to those obtained by one-photon excitation, which may indicate that the two-photon induced photodynamic processes of hypocrellins are similar to one-photon induced photodynamic processes. The two-photon excitation cross sections of HA and HB are measured at 800 nm as about 34.8 X 10(-5)0 cm(4) s /photon and 21.3 X 10(-50) cm(4) s/photon, respectively. The large two-photon cross sections of both HA and HB, suggest that the hypocrellins can be potential two-photon phototherapeutic agents. As an example for two-photon photodynamic therapy of hypocrellins, we also further examine the cell-damaging effects of HA upon two-photon illumination. Our preliminary results of cell viability test indicate hypocrellins can effectively damage the Hela cells under two-photon illumination. (C) 2002 Elsevier Science B.V. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000179892100013 |
| 出版者 | ELSEVIER SCIENCE SA |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/78191]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Xia, AD |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100080, Peoples R China 3.Univ Sci & Technol China, Dept Biol, Hefei 230026, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, J,Zhao, YW,Zhao, JQ,et al. Two-photon excitation studies of hypocrellins for photodynamic therapy[J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY,2002,68(2-3):156-164. |
| APA | Liu, J.,Zhao, YW.,Zhao, JQ.,Xia, AD.,Jiang, LJ.,...&Dong, YQ.(2002).Two-photon excitation studies of hypocrellins for photodynamic therapy.JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY,68(2-3),156-164. |
| MLA | Liu, J,et al."Two-photon excitation studies of hypocrellins for photodynamic therapy".JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY 68.2-3(2002):156-164. |
入库方式： OAI收割
来源：化学研究所
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