Spectroscopic investigation on the telomeric DNA base sequence repeat
文献类型：期刊论文
| 作者 | Xu, SC; Al, XC; Sun, ZY; Zhang, QY; Zhang, XK |
| 刊名 | CHINESE SCIENCE BULLETIN
 |
| 出版日期 | 2002 |
| 卷号 | 47期号:2页码:108-111 |
| 关键词 | Dna Telomere Oligonucleotide Fluorescence Quantum Yield |
| ISSN号 | 1001-6538 |
| 英文摘要 | Telomeres are protein-DNA complexes at the terminals of linear chromosomes, which protect chromosomal integrity and maintain cellular replicative capacity. From single-cell organisms to advanced animals and plants, structures and functions of telomeres are both very conservative. In cells of human and vertebral animals, telomeric DNA base sequences all are (TTAGGG). In the present work, we have obtained absorption and fluorescence spectra measured from seven synthesized oligonucleotides to simulate the telomeric DNA system and calculated their relative fluorescence quantum yields on which not only telomeric DNA characteristics are predicted but also possibly the shortened telomeric sequences during cell division are implied. Oligonucleotide 5'- TTAGGGTTAGGG holds a low relative fluorescence quantum yield and remarkable excitation energy innerconversion, which tallies with the telomeric sequence of (TTAGGG). This result shows that telomeric DNA has a strong non-radiative or innerconvertible, capability. |
| 语种 | 英语 |
| WOS记录号 | WOS:000174261900006 |
| 出版者 | SCIENCE CHINA PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/78279]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Xu, SC |
| 作者单位 | Chinese Acad Sci, Inst Chem, State Key Lab Struct Chem Unstable & Stable Speci, Ctr Mol Sci, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, SC,Al, XC,Sun, ZY,et al. Spectroscopic investigation on the telomeric DNA base sequence repeat[J]. CHINESE SCIENCE BULLETIN,2002,47(2):108-111. |
| APA | Xu, SC,Al, XC,Sun, ZY,Zhang, QY,&Zhang, XK.(2002).Spectroscopic investigation on the telomeric DNA base sequence repeat.CHINESE SCIENCE BULLETIN,47(2),108-111. |
| MLA | Xu, SC,et al."Spectroscopic investigation on the telomeric DNA base sequence repeat".CHINESE SCIENCE BULLETIN 47.2(2002):108-111. |
入库方式： OAI收割
来源：化学研究所
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