Hydrolysis of phospholipid and possible mechanism of gallstone formation
文献类型:期刊论文
作者 | Xu, YZ; Somjen, G; Yang, ZL; Weng, SF; Liu, HW; Li, WH; Zhang, X; Wu, JG; Xu, DF |
刊名 | ACTA CHIMICA SINICA
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出版日期 | 2002-04-01 |
卷号 | 60期号:4页码:711-714 |
关键词 | Ft-ir Phospholipid Cholesterol Gallstone |
ISSN号 | 0567-7351 |
英文摘要 | Taurocholic salt-phospholipid-cholesterol-water solubilized systems were used to investigate the physical/chemical behavior of bile. Phase separation that produces float and precipitation was observed in the system. Analysis using FT-IR spectroscopy and GC-MS methods showed that aliphatic acids were principal component of the float. This demonstrated that hydrolysis of phospholipid must have occurred in the system. Considering that phospholipid plays a very important role in solubilizing cholesterol in bile, whereas aliphatic acids can not solubilize cholesterol, we suggest that the hydrolysis of phospholipid may be related to the formation of gallstone. |
语种 | 英语 |
WOS记录号 | WOS:000175079300029 |
出版者 | SCIENCE CHINA PRESS |
源URL | [http://ir.iccas.ac.cn/handle/121111/78901] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Xu, YZ |
作者单位 | 1.Peking Univ, Dept Chem, State Key Lab Rare Earth Mat Chem & Applicat, Beijing 100871, Peoples R China 2.Chinese Acad Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100080, Peoples R China |
推荐引用方式 GB/T 7714 | Xu, YZ,Somjen, G,Yang, ZL,et al. Hydrolysis of phospholipid and possible mechanism of gallstone formation[J]. ACTA CHIMICA SINICA,2002,60(4):711-714. |
APA | Xu, YZ.,Somjen, G.,Yang, ZL.,Weng, SF.,Liu, HW.,...&Xu, DF.(2002).Hydrolysis of phospholipid and possible mechanism of gallstone formation.ACTA CHIMICA SINICA,60(4),711-714. |
MLA | Xu, YZ,et al."Hydrolysis of phospholipid and possible mechanism of gallstone formation".ACTA CHIMICA SINICA 60.4(2002):711-714. |
入库方式: OAI收割
来源:化学研究所
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