Effect of exhausting exercise on amino acid neurotransmitters in hypothalamus of rats
文献类型：期刊论文
| 作者 | Zhang, DM; Zhang, JM; Ma, WY; Chen, DY; Han, HW; Shu, HJ; Liu, GQ |
| 刊名 | CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
 |
| 出版日期 | 2002-02-01 |
| 卷号 | 23期号:2页码:230-233 |
| 关键词 | Microdialysis Amino Acid Neurotransmitter Exercise |
| ISSN号 | 0251-0790 |
| 英文摘要 | A simple and effective coupling of microdialysis and capillary electrophoresis with laser induced fluorescence detection technique was applied to the analysis of amino acid neurotransmitters in hypothalamus of rat after an acute exhausting exercise. The separation of amino acids was achieved by using an un-coated fused silica capillary (57 cm X 75 mum i.d.) with a buffer of 10 mmol/L disodium tetraborate at pH 10 and an applied voltage of 12. 5 kV. The detection limit was 10(-10) mol/L for each amino acid. It is sufficiently sensitive and rapid for the determination of amino acid in 5 muL Microdialysate. In comparison to pre-exercise, a significant increase in the levels of 6 hypothalamic amino acids(arginine, glycine, lysine, glutamic acid, alanine, gamma-amino-n-butyric acid) after exercise was found. These results demonstrate that increase of metabolic amino acids in hypothalamus of rats can be induced by exhaustive exercise and suggesting that amino acid neurotransmitters may play functional roles in the central effects of exercise. |
| 语种 | 英语 |
| WOS记录号 | WOS:000174163300018 |
| 出版者 | HIGHER EDUCATION PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/79133]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Ma, WY |
| 作者单位 | 1.Tsing Hua Univ, Dept Phys, Key Lab Atom & Mol Nanosci, Educ Minist, Beijing 100084, Peoples R China 2.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, DM,Zhang, JM,Ma, WY,et al. Effect of exhausting exercise on amino acid neurotransmitters in hypothalamus of rats[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2002,23(2):230-233. |
| APA | Zhang, DM.,Zhang, JM.,Ma, WY.,Chen, DY.,Han, HW.,...&Liu, GQ.(2002).Effect of exhausting exercise on amino acid neurotransmitters in hypothalamus of rats.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,23(2),230-233. |
| MLA | Zhang, DM,et al."Effect of exhausting exercise on amino acid neurotransmitters in hypothalamus of rats".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 23.2(2002):230-233. |
入库方式： OAI收割
来源：化学研究所
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