Novel ultrasound contrast agents - Biodegradable poly(lactic acid) microcapsules
文献类型：期刊论文
| 作者 | Wang, SG; Cui, WJ; Li, GM; Cai, Q; Zhi, G; Zhao, YY; Yang, B; Xu, Y |
| 刊名 | SCIENCE IN CHINA SERIES B-CHEMISTRY
 |
| 出版日期 | 2003-08-01 |
| 卷号 | 46期号:4页码:371-378 |
| 关键词 | Poly(Lactic Acid) Microcapsules Contrast Agent Ultrasound Diagnosis Blood Filters |
| ISSN号 | 1006-9291 |
| DOI | 10.1360/02yb0194 |
| 英文摘要 | As a novel ultrasound diagnostic contrast agent, the preparation, characterization and ultrasound imaging in the body of dog about poly(lactic acid) (PLLA) microcapsules have been studied. The behavior of this kind of contrast agent in the microcirculation was also investigated. Prepared by (water/oil/water) emulsion-solvent evaporation protocol, the PLLA microcapsules with hollow structure can enhance the ultrasound image both in vitro and in vivo, and the enduring time can last as long as 3 h. The microcirculation examination shows that the PLLA microcapsules with a diameter ranging from 2 to 8 mum could pass through the pulmonary capillaries without retention. All the results prove the PLLA microcapsules for potential use for the clinical application. |
| 语种 | 英语 |
| WOS记录号 | WOS:000184931000006 |
| 出版者 | SCIENCE CHINA PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/79637]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, SG |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China 2.Gen Hosp Peoples Liberat Army, Beijing 100853, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, SG,Cui, WJ,Li, GM,et al. Novel ultrasound contrast agents - Biodegradable poly(lactic acid) microcapsules[J]. SCIENCE IN CHINA SERIES B-CHEMISTRY,2003,46(4):371-378. |
| APA | Wang, SG.,Cui, WJ.,Li, GM.,Cai, Q.,Zhi, G.,...&Xu, Y.(2003).Novel ultrasound contrast agents - Biodegradable poly(lactic acid) microcapsules.SCIENCE IN CHINA SERIES B-CHEMISTRY,46(4),371-378. |
| MLA | Wang, SG,et al."Novel ultrasound contrast agents - Biodegradable poly(lactic acid) microcapsules".SCIENCE IN CHINA SERIES B-CHEMISTRY 46.4(2003):371-378. |
入库方式： OAI收割
来源：化学研究所
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