Hyperoxia caused by microdialysis perfusion decreased striatal monoamines: involvement of oxidative stress
文献类型：期刊论文
| 作者 | Wang, L; Osborne, PG; Yu, X; Shangguan, D; Zhao, R; Han, HW; Liu, GQ |
| 刊名 | NEUROCHEMISTRY INTERNATIONAL
 |
| 出版日期 | 2003-05-01 |
| 卷号 | 42期号:6页码:465-470 |
| 关键词 | Dopamine Oxygen Tension Hyperoxia Oxidative Stress |
| ISSN号 | 0197-0186 |
| 英文摘要 | Due to complex influence, such as utilization and permeability of arterial vessels to oxygen, there is a considerable difference of oxygen tension between extracellular fluid and perfusate usually used in microdialysis (30-60 Torr versus 145 Torr). Dialysate dopamine and monoamine metabolites-3,4-dihydroxyphenylacetic acid, homovanillic acid and 5-hydroxyindoleacetic acid were measured under different kinds of oxygen tension solutions (145, 72, 48 Torr). In the acute and anesthetized group, dopamine, 3,4-dihydroxyphenylacetic acid, 5-hydroxyindoleacetic acid and homovanillic acid increased 72, 93, 86 and 65%, respectively when changing the perfusate from 145 Torr to near physiological 48 Torr, while in chronic and conscious group, carried out 72 h after surgery, these compounds showed obscure increases (only homovanillic acid produced a significant change of 14%). |
| 语种 | 英语 |
| WOS记录号 | WOS:000181510800004 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/80239]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Liu, GQ |
| 作者单位 | Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, L,Osborne, PG,Yu, X,et al. Hyperoxia caused by microdialysis perfusion decreased striatal monoamines: involvement of oxidative stress[J]. NEUROCHEMISTRY INTERNATIONAL,2003,42(6):465-470. |
| APA | Wang, L.,Osborne, PG.,Yu, X.,Shangguan, D.,Zhao, R.,...&Liu, GQ.(2003).Hyperoxia caused by microdialysis perfusion decreased striatal monoamines: involvement of oxidative stress.NEUROCHEMISTRY INTERNATIONAL,42(6),465-470. |
| MLA | Wang, L,et al."Hyperoxia caused by microdialysis perfusion decreased striatal monoamines: involvement of oxidative stress".NEUROCHEMISTRY INTERNATIONAL 42.6(2003):465-470. |
入库方式： OAI收割
来源：化学研究所
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