热门
Biodegradable electrospun fibers for drug delivery
文献类型：期刊论文
| 作者 | Jing, Z; Xu, XY; Chen, XS; Liang, QZ; Bian, XC; Yang, LX; Jing, XB |
| 刊名 | JOURNAL OF CONTROLLED RELEASE
 |
| 出版日期 | 2003-10-30 |
| 卷号 | 92期号:3页码:227-231 |
| 关键词 | Drug Delivery Electrospinning Ultrafine Fibers |
| ISSN号 | 0168-3659 |
| DOI | 10.1016/S0168-3659(03)00372-9 |
| 英文摘要 | The influences of surfactants and medical drugs on the diameter size and uniformity of electrospun poly(L-lactic acid) (PLLA) fibers were examined by adding various surfactants (cationic, anionic, and nonionic) and typical drugs into the PLLA solution. Significant diameter reduction and uniformity improvement were observed. It was shown that the drugs were capsulated inside of the fibers and the drug release in the presence of proteinase K followed nearly zero-order kinetics due to the degradation of the PLLA fibers. Such ultrafine fiber mats containing drugs may find clinical applications in the future. (C) 2003 Elsevier B.V. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000186260200001 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/80811]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Jing, XB |
| 作者单位 | Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jing, Z,Xu, XY,Chen, XS,et al. Biodegradable electrospun fibers for drug delivery[J]. JOURNAL OF CONTROLLED RELEASE,2003,92(3):227-231. |
| APA | Jing, Z.,Xu, XY.,Chen, XS.,Liang, QZ.,Bian, XC.,...&Jing, XB.(2003).Biodegradable electrospun fibers for drug delivery.JOURNAL OF CONTROLLED RELEASE,92(3),227-231. |
| MLA | Jing, Z,et al."Biodegradable electrospun fibers for drug delivery".JOURNAL OF CONTROLLED RELEASE 92.3(2003):227-231. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。