Unmatched masses in peptide mass fingerprints caused by cross-contamination: An updated statistical result
文献类型：期刊论文
| 作者 | Ding, QX; Xiao, L; Xiong, SX; Jia, YF; Que, HP; Guo, YJ; Liu, SJ |
| 刊名 | PROTEOMICS
 |
| 出版日期 | 2003-07-01 |
| 卷号 | 3期号:7页码:1313-1317 |
| 关键词 | Cross Contamination Keratins Peptide Mass Fingerprint |
| ISSN号 | 1615-9853 |
| DOI | 10.1002/pmic.200300452 |
| 英文摘要 | Unmatched masses are often observed in the experimental peptide mass spectra when database searching is performed with the ProFound program. Comparison between theoretical and experimental mass spectra of standard proteins shows that contamination accounts for most of the unmatched masses. In this retrospective analysis, the top 100 most probable contaminating masses, as listed in order of their probability, are statistically filtered out from 118 different experimental peptide mass fingerprinting (PMF) maps. Most of the interfering masses originate from trypsin autolysis and human keratins. Subtraction of known contaminants from raw data and using cleaner masses for searching can enhance protein identification by PMF |
| 语种 | 英语 |
| WOS记录号 | WOS:000184507200023 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/80929]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Liu, SJ |
| 作者单位 | 1.Chinese Acad Med Sci, Inst Basic Med Sci, Dept Neurobiol, Beijing 100850, Peoples R China 2.Beijing Mass Spectronomy Ctr, Inst Chem, Beijing, Peoples R China 3.Inst Biophys, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ding, QX,Xiao, L,Xiong, SX,et al. Unmatched masses in peptide mass fingerprints caused by cross-contamination: An updated statistical result[J]. PROTEOMICS,2003,3(7):1313-1317. |
| APA | Ding, QX.,Xiao, L.,Xiong, SX.,Jia, YF.,Que, HP.,...&Liu, SJ.(2003).Unmatched masses in peptide mass fingerprints caused by cross-contamination: An updated statistical result.PROTEOMICS,3(7),1313-1317. |
| MLA | Ding, QX,et al."Unmatched masses in peptide mass fingerprints caused by cross-contamination: An updated statistical result".PROTEOMICS 3.7(2003):1313-1317. |
入库方式： OAI收割
来源：化学研究所
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