Synthesis of new dendritic chiral BINOL ligands and their applications in enantioselective Lewis acid catalyzed addition of diethylzinc to aldehydes
文献类型：期刊论文
| 作者 | Fan, QH; Yang, XQ; Liu, GG; Chen, XM; Chan, ASC |
| 刊名 | CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
 |
| 出版日期 | 2003-02-01 |
| 卷号 | 24期号:2页码:274-277 |
| 关键词 | Chiral Dendrimer Asymmetric Catalysis 1 1 '-binol |
| ISSN号 | 0251-0790 |
| 英文摘要 | The series of new dendritic chiral BINOL ligands(3) were synthesized by condensation reaction of (R)-2,2'-dihydroxy-1,1'-binaphthyl-3,3'-dicarboxylic acid(1) and Frechet-type poly(aryl ether) dendrons(2) with an amino group at the focal point in moderate reaction yields. All ligands were characterized by H-1 NMR, IR and MALDI-TOF-MS spectra, which clearly demonstrated the formation of monodispersed dendritic BINOLs. The titanium complexes of these dendritic ligands obtained by mixing(3) with Ti(OPri)(4) in dry toluene were found to be efficient catalysts in asymmetric addition of diethylzinc to aldehydes. The size of the dendritic wedges did not significantly influence the enantioselectivity of the catalyst. Most interestingly, when ortho-chlorobenzaldehyde was used as substrate, we found that enantioselectivity increased slightly with increasing generation of the dendrimers. |
| 语种 | 英语 |
| WOS记录号 | WOS:000182543000021 |
| 出版者 | HIGHER EDUCATION PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/81405]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Fan, QH |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China 2.Open Lab Chirotechnol, Hong Kong, Hong Kong, Peoples R China 3.Dept Appl Biol & Chem Technol, Hong Kong, Hong Kong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Fan, QH,Yang, XQ,Liu, GG,et al. Synthesis of new dendritic chiral BINOL ligands and their applications in enantioselective Lewis acid catalyzed addition of diethylzinc to aldehydes[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2003,24(2):274-277. |
| APA | Fan, QH,Yang, XQ,Liu, GG,Chen, XM,&Chan, ASC.(2003).Synthesis of new dendritic chiral BINOL ligands and their applications in enantioselective Lewis acid catalyzed addition of diethylzinc to aldehydes.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,24(2),274-277. |
| MLA | Fan, QH,et al."Synthesis of new dendritic chiral BINOL ligands and their applications in enantioselective Lewis acid catalyzed addition of diethylzinc to aldehydes".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 24.2(2003):274-277. |
入库方式： OAI收割
来源：化学研究所
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