Cell adhesion on gaseous plasma modified poly-(L-lactide) surface under shear stress field
文献类型：期刊论文
| 作者 | Wan, YQ; Yang, J; Yang, JL; Bei, JZ; Wang, SG |
| 刊名 | BIOMATERIALS
 |
| 出版日期 | 2003-09-01 |
| 卷号 | 24期号:21页码:3757-3764 |
| 关键词 | Poly-(L-lactide) Plasma Treatment Surface Modification Shear Stress Tissue Engineering |
| ISSN号 | 0142-9612 |
| DOI | 10.1016/S0142-9612(03)00251-2 |
| 英文摘要 | A series of gases were used for plasma treatment of poly-(L-lactide) (PLLA) under various conditions such as atmosphere, electric power, pressure and time. The NH3 was preferably selected for modifying the surface of PLLA because it can obtain appropriate hydrophilicity and surface energy with high polar component compared to other gases. Subsequently, cells were seeded onto NH3 modified surface and exposed to 29.5 N/m(2) of shear stress field by means of a parallel plate flow chamber in order to get good insight into the influence of N-containing incorporation on cell retention, cell morphology, and cell shape factor. The results showed that cell retention on the modified PLLA was much higher than that on the unmodified one. The NH3 plasma modified PLLA with high cell affinity and resistance to shear stress was gained. Surface hydrophilicity, surface energy with high polar component and N-containing groups may play an important role in enhancing cell resistance to shear stress. It revealed that the parallel plate flow chamber is an effective device for evaluating the effects of surface modification on the cell affinity of a material. (C) 2003 Elsevier Science Ltd. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000183992700014 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/81467]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, SG |
| 作者单位 | Chinese Acad Sci, Inst Chem, Ctr Mol Sci, State Key Lab Polymer Phys & Chem, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wan, YQ,Yang, J,Yang, JL,et al. Cell adhesion on gaseous plasma modified poly-(L-lactide) surface under shear stress field[J]. BIOMATERIALS,2003,24(21):3757-3764. |
| APA | Wan, YQ,Yang, J,Yang, JL,Bei, JZ,&Wang, SG.(2003).Cell adhesion on gaseous plasma modified poly-(L-lactide) surface under shear stress field.BIOMATERIALS,24(21),3757-3764. |
| MLA | Wan, YQ,et al."Cell adhesion on gaseous plasma modified poly-(L-lactide) surface under shear stress field".BIOMATERIALS 24.21(2003):3757-3764. |
入库方式： OAI收割
来源：化学研究所
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