Mechanism of intramolecular charge transfer in DNA helix as probed by the use of the fluorescent 2-aminopurine
文献类型：期刊论文
| 作者 | Zhang, HJ; Wang, P; Wang, XF; Feng, J; Xu, SC; Al, X; Zhang, XK; Zhang, JP |
| 刊名 | SCIENCE IN CHINA SERIES B-CHEMISTRY
 |
| 出版日期 | 2004-10-01 |
| 卷号 | 47期号:5页码:367-372 |
| 关键词 | 2-aminopurine (2ap) Dna Charge Transfer Time-resolved Fluorescence Spectroscopy |
| ISSN号 | 1006-9291 |
| 英文摘要 | As a structural analogue of adenine, 2-aminopurine (2Ap) is often used as a fluorescent probe to study the intramolecular charge transfer reaction in DNA. We have designed and synthesized a series of model DNA helix with the variation in the distance between the 2Ap probe and the GGG sequence, and have investigated, by means of picosecond time-resolved fluorescence spectroscopy, the effect of the length of the bridge (consisting of a number of inosines, 1) separating the electron donor (... GGG...) and the acceptor (2Ap) on the charge transfer dynamics. The fluorescence dynamics of 2Ap exhibited three exponential decay components, the one with a time constant of a few hundred picoseconds is assigned to the intramolecular charge transfer from GGG to 2Ap. Within 2.4 nm of the donor-acceptor separation, the rate of charge transfer decreased exponentially upon increasing the separation, from which the decay factor beta is determined to be 1.3 nm(-1). Beyond 2.4 nm, however, the rate started to increase, this abnormal behavior of charge transfer is interpreted in terms of the match of electronic energies between the 1-bridge and the donor/acceptor couple. |
| 语种 | 英语 |
| WOS记录号 | WOS:000225425000002 |
| 出版者 | SCIENCE CHINA PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/81933]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Al, X |
| 作者单位 | Chinese Acad Sci, Inst Chem, State Key Lab Struct Chem Unstable & Stable Speci, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, HJ,Wang, P,Wang, XF,et al. Mechanism of intramolecular charge transfer in DNA helix as probed by the use of the fluorescent 2-aminopurine[J]. SCIENCE IN CHINA SERIES B-CHEMISTRY,2004,47(5):367-372. |
| APA | Zhang, HJ.,Wang, P.,Wang, XF.,Feng, J.,Xu, SC.,...&Zhang, JP.(2004).Mechanism of intramolecular charge transfer in DNA helix as probed by the use of the fluorescent 2-aminopurine.SCIENCE IN CHINA SERIES B-CHEMISTRY,47(5),367-372. |
| MLA | Zhang, HJ,et al."Mechanism of intramolecular charge transfer in DNA helix as probed by the use of the fluorescent 2-aminopurine".SCIENCE IN CHINA SERIES B-CHEMISTRY 47.5(2004):367-372. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。