In vivo and rapid detection of the malignancy tumor of oral tissues using Mid-FTIR fiber optics spectroscopy
文献类型：期刊论文
| 作者 | Xu, YZ; Zhang, YF; Yang, LM; Peng, X; Sun, KH; Li, QB; Zhou, WJ; Wu, HZ; Yu, GY; Liu, Z |
| 刊名 | CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
 |
| 出版日期 | 2004-02-01 |
| 卷号 | 25期号:2页码:348-350 |
| 关键词 | Mid-ir Fiber Optics Ftir Malignancy Tumor Of Oral Tissue In Vivo And In Situ Detection |
| ISSN号 | 0251-0790 |
| 英文摘要 | Our previous studies show that mid-FTIR spectroscopy can be used to distinguish malignant oral tissue from normal tissue under in vitro condition. Here, an in-situ FTIR spectroscopic measurement was performed to record FTIR spectra of normal and malignant oral tissues including salivary gland, tongue, parotid gland, submandibular gland etc. during clinical examination. The FTIR spectra of various oral tissues were acquired when an ATR probe linked to the FTIR. spectrometer via mid-IR optical fibers was pressed on the tissues of the patients. For example, a patient(male, 76 years old) with tumor on the left parotid and the corresponding normal tissue on the right parotid were measured and obvious differences were observed. The spectral features of normal tissue and tumor are in good agreement with the criteria established in our previous work. (1) 1389 cm(-1) band is quite strong in tumor, while the corresponding band in normal tissue is weaker than 1452 cm(-1) band. (2) In normal tissue, 1250 cm(-1) band is stronger, but the 1250 cm(-1) band disappeared in the skin. of malignant tissue. The above results demonstrate that in vivo FTIR spectra are in good agreement with our previous results obtained under in vitro condition. We believe that in vivo FTIR spectroscopy, providing the first-hand information concerning whether the suspected tissue is cancerous or not, is helpful for doctors in clinical activity. |
| 语种 | 英语 |
| WOS记录号 | WOS:000189187400039 |
| 出版者 | HIGHER EDUCATION PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/81973]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Xu, YZ |
| 作者单位 | 1.Peking Univ, State Key Lab Rare Earth Mat & Applicat, Coll Chem & Mol Engn, Beijing 100871, Peoples R China 2.Peking Univ, Med Sch Stomatol, Beijing 100081, Peoples R China 3.Beijing Secondary Opt Instrument Factory, Beijing 100015, Peoples R China 4.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, YZ,Zhang, YF,Yang, LM,et al. In vivo and rapid detection of the malignancy tumor of oral tissues using Mid-FTIR fiber optics spectroscopy[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2004,25(2):348-350. |
| APA | Xu, YZ.,Zhang, YF.,Yang, LM.,Peng, X.,Sun, KH.,...&Wu, JG.(2004).In vivo and rapid detection of the malignancy tumor of oral tissues using Mid-FTIR fiber optics spectroscopy.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,25(2),348-350. |
| MLA | Xu, YZ,et al."In vivo and rapid detection of the malignancy tumor of oral tissues using Mid-FTIR fiber optics spectroscopy".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 25.2(2004):348-350. |
入库方式： OAI收割
来源：化学研究所
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