A novel water-soluble nanoparticles of hypocrellin B and their interaction with a model protein: C-phycocyanin
文献类型：期刊论文
| 作者 | Zhao, BZ; Xie, H; Zhao, JQ |
| 刊名 | BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
 |
| 出版日期 | 2004-01-22 |
| 卷号 | 1670期号:2页码:113-120 |
| 关键词 | Hypocrellin b Gelatin Nanoparticle C-phycocyanin Complex Energy Transfer Reactive Oxygen Species Photo-damage |
| ISSN号 | 0304-4165 |
| DOI | 10.1016/j.bbagen.2003.10.018 |
| 英文摘要 | A type of novel hypocrellin B gelatin nanoparticles (HB-G-NP), with size of 20-200 nm, was prepared and characterized. The nanoparticles are readily soluble in water or phosphate-buffered saline (PBS). The interaction between HB-G-NP and a fluorescence protein, C-phycocyanin (C-PC) from Spirulina platensis, was studied. It was found that the energy transfer from HB to C-PC was quite efficient, suggesting adsorption of C-PC on surface of the nanoparticles; secondly, the photosensitization of HB resulted in not only the photo-damage of C-PC but also the photobleaching of HB in the presence of oxygen while it did not in the absence of oxygen, suggesting that the movable reactive oxygen species, instead of the immovable anionic radicals of the photosensitizer, should be responsible for the photo-induced processes. Considering the short free diffusion path length of the reactive oxygen species, it can be deduced that smaller or ring-like particles should be more effective for photo-damage of biomolecules or target tissues. (C) 2003 Elsevier B.V. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000188537900003 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/82059]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zhao, JQ |
| 作者单位 | Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Key Lab Photochem, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, BZ,Xie, H,Zhao, JQ. A novel water-soluble nanoparticles of hypocrellin B and their interaction with a model protein: C-phycocyanin[J]. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,2004,1670(2):113-120. |
| APA | Zhao, BZ,Xie, H,&Zhao, JQ.(2004).A novel water-soluble nanoparticles of hypocrellin B and their interaction with a model protein: C-phycocyanin.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,1670(2),113-120. |
| MLA | Zhao, BZ,et al."A novel water-soluble nanoparticles of hypocrellin B and their interaction with a model protein: C-phycocyanin".BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1670.2(2004):113-120. |
入库方式： OAI收割
来源：化学研究所
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