Fluorescence response of hypocrellin B to the environmental changes in a mimic biological membrane - liposome
文献类型：期刊论文
| 作者 | Jin, XY; Zhao, YW; Xie, J; Zhao, JQ |
| 刊名 | SCIENCE IN CHINA SERIES B-CHEMISTRY
 |
| 出版日期 | 2004-08-01 |
| 卷号 | 47期号:4页码:335-339 |
| 关键词 | Microenvironment Hypocrellin b Liposome Fluorescence |
| ISSN号 | 1006-9291 |
| DOI | 10.1360/03yb0190 |
| 英文摘要 | Liposome is well known as not only a drug-delivery system but also a simple model for biological membranes. It was reported that fluorescence properties of hypocrellins were changeable over some extreme pH values. In the current work, the effects of the microenvironments on the fluorescence properties of HB in liposome, including approximately physiological range of pH values pH = 6.0-8.0, concentration of cholesterols and ionic strength of the solution, were studied. It was found that the fluorescence intensity of HB was sensitive to and also regulated by the microenvironments. When concentration of cholesterols and ionic strength keep invariable in PBS solution, there exists the maximum for the fluorescence of HB-liposome at pH 7.4 while the minimum for that of HB at pH 7.0. In addition, when pH value keeps constant (7.2), there exists the maximum at the ionic strength of 0.12 mol/kg while that at the concentration of 6x10(-4) mol/L for cholesterols. On the other hand, in PBS solution, the lower the ionic strength is, the higher the fluorescence intensity is. The environment-sensitive fluorescence may be potentially applicable to probe some specific environmental features in cells or tissues. |
| 语种 | 英语 |
| WOS记录号 | WOS:000224391900010 |
| 出版者 | SCIENCE CHINA PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/82181]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zhao, JQ |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, CAS Key Lab Photochem, Beijing 100080, Peoples R China 2.China Univ Geosci, Sch Earth Sci & Resources, Beijing 100083, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jin, XY,Zhao, YW,Xie, J,et al. Fluorescence response of hypocrellin B to the environmental changes in a mimic biological membrane - liposome[J]. SCIENCE IN CHINA SERIES B-CHEMISTRY,2004,47(4):335-339. |
| APA | Jin, XY,Zhao, YW,Xie, J,&Zhao, JQ.(2004).Fluorescence response of hypocrellin B to the environmental changes in a mimic biological membrane - liposome.SCIENCE IN CHINA SERIES B-CHEMISTRY,47(4),335-339. |
| MLA | Jin, XY,et al."Fluorescence response of hypocrellin B to the environmental changes in a mimic biological membrane - liposome".SCIENCE IN CHINA SERIES B-CHEMISTRY 47.4(2004):335-339. |
入库方式： OAI收割
来源：化学研究所
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