Magnograndins J-M, elemane sesquiterpenoids from the leaves of Magnolia grandiflora and their inhibitory effects on nitric oxide production
文献类型：期刊论文
| 作者 | Ding, Lin-Fen1,2,3; Liu, Jiang-Xin1; Xie, Zhang-Qiao1,2,3; Wang, De-Shen1,2,3; Nie, Wei1,2,3; Song, Liu-Dong2,3; Wu, Xing-De1; Zhao, Qin-Shi1
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| 刊名 | PHYTOCHEMISTRY LETTERS
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| 出版日期 | 2019-06-01 |
| 卷号 | 31页码:121-124 |
| 关键词 | Magnolia grandiflora Elemane sesquiterpenoid Nitric oxide (NO) |
| ISSN号 | 1874-3900 |
| DOI | 10.1016/j.phytol.2019.03.021 |
| 通讯作者 | Wu, Xing-De(wuxingde@mail.kib.ac.cn) ; Zhao, Qin-Shi(qinshizhao@mail.kib.ac.cn) |
| 英文摘要 | Four new elemane sesquiterpenoids, magnograndins J-M (1-4), and one known sesquiterpenoid, 12,13-diacetoxyelema-1,3-dien-6 alpha,11-diol (5), were obtained from 70% acetone extract of the leaves of Magnolia grandiflora. Their structures were determined with extensive spectroscopic (HRMS, IR, 1D and 2D NMR) analyses. Compound 1 represented the first example of elemane sesquiterpenoid with an orthoacetate unit. Compound 4 inhibited nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells with IC50 value of 17.83 mu M. |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000469429200022 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/67423]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Wu, Xing-De; Zhao, Qin-Shi |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Kunming Med Univ, Sch Pharmaceut Sci, Kunming 650500, Yunnan, Peoples R China 3.Kunming Med Univ, Yunnan Key Lab Pharmacol Nat Prod, Kunming 650500, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ding, Lin-Fen,Liu, Jiang-Xin,Xie, Zhang-Qiao,et al. Magnograndins J-M, elemane sesquiterpenoids from the leaves of Magnolia grandiflora and their inhibitory effects on nitric oxide production[J]. PHYTOCHEMISTRY LETTERS,2019,31:121-124. |
| APA | Ding, Lin-Fen.,Liu, Jiang-Xin.,Xie, Zhang-Qiao.,Wang, De-Shen.,Nie, Wei.,...&Zhao, Qin-Shi.(2019).Magnograndins J-M, elemane sesquiterpenoids from the leaves of Magnolia grandiflora and their inhibitory effects on nitric oxide production.PHYTOCHEMISTRY LETTERS,31,121-124. |
| MLA | Ding, Lin-Fen,et al."Magnograndins J-M, elemane sesquiterpenoids from the leaves of Magnolia grandiflora and their inhibitory effects on nitric oxide production".PHYTOCHEMISTRY LETTERS 31(2019):121-124. |
入库方式： OAI收割
来源：昆明植物研究所
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