Investigation of the fine structure around the copper site in copper/zinc superoxide dismutase by XANES combined with ab initio calculations
文献类型：期刊论文
| 作者 | Wei, XJ; Chu SQ(储胜启) ; Zhao HF(赵海峰); Chu, WS; Zhao, HF; Cui, PX; Huang, YY; Jiang, Z; Wang, Y; Zhang, S
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| 刊名 | RADIATION PHYSICS AND CHEMISTRY
 |
| 出版日期 | 2017 |
| 卷号 | 137页码:88-92 |
| 关键词 | Copper/zinc superoxide dismutase BioXAS Metalloprotein MXAN |
| ISSN号 | 0969-806X |
| DOI | 10.1016/j.radphyschem.2016.03.003 |
| 文献子类 | Article; Proceedings Paper |
| 英文摘要 | Copper/zinc superoxide dismutase (CuZnSOD) is an important enzyme that plays a crucial role in protecting oxygen-metabolizing cells against harmful effects of superoxide free-radicals. In this work, the three-dimensional local structure around the copper-binding site in pH 7.0 buffer solution was determined using X-ray absorption near-edge spectroscopy (XANES) combined with ab initio calculations in the framework of the multiple-scattering theory performed by MXAN. Extremely accurate bond distances and bond angle information between ligands were returned. The result confirmed that the copper ion binds four conserved His residues and a water molecule in CuZnSOD and prefers a five-coordinated in a distorted square pyramidal geometry. (C) 2016 Elsevier Ltd. All rights reserved. |
| 会议地点 | Univ Sci & Technol China, Beijing, PEOPLES R CHINA |
| WOS关键词 | X-RAY-ABSORPTION ; AMYOTROPHIC-LATERAL-SCLEROSIS ; IRON-MOLYBDENUM COFACTOR ; NEAR-EDGE STRUCTURE ; K-EDGE ; SPECTRA ; SPECTROSCOPY ; NITROGENASE ; IFEFFIT |
| 会议日期 | SEP 07-11, 2015 |
| WOS研究方向 | Chemistry ; Nuclear Science & Technology ; Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000404201800018 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/284924]  |
| 专题 | 高能物理研究所_多学科研究中心 高能物理研究所_粒子天体物理中心 |
| 作者单位 | 中国科学院高能物理研究所 |
| 推荐引用方式 GB/T 7714 | Wei, XJ,Chu SQ,Zhao HF,et al. Investigation of the fine structure around the copper site in copper/zinc superoxide dismutase by XANES combined with ab initio calculations[J]. RADIATION PHYSICS AND CHEMISTRY,2017,137:88-92. |
| APA | Wei, XJ.,储胜启.,赵海峰.,Chu, WS.,Zhao, HF.,...&Jin, S.(2017).Investigation of the fine structure around the copper site in copper/zinc superoxide dismutase by XANES combined with ab initio calculations.RADIATION PHYSICS AND CHEMISTRY,137,88-92. |
| MLA | Wei, XJ,et al."Investigation of the fine structure around the copper site in copper/zinc superoxide dismutase by XANES combined with ab initio calculations".RADIATION PHYSICS AND CHEMISTRY 137(2017):88-92. |
入库方式： OAI收割
来源：高能物理研究所
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